ARHGAP5 and RND2

Data Source:
BioGRID (pull down)

		ARHGAP5	RND2
Description		Rho GTPase activating protein 5	Rho family GTPase 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Cytosol Plasma Membrane	Acrosomal Membrane Early Endosome Cytoskeleton Plasma Membrane Cell Cortex Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle
	Molecular Function	GTPase Activity GTPase Activator Activity Protein Binding GTP Binding SH2 Domain Binding	GTPase Activity Protein Binding GTP Binding Protein Kinase Binding Protein N-terminus Binding
	Biological Process	Cell Adhesion Rho Protein Signal Transduction Mammary Gland Development Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Signal Transduction Small GTPase Mediated Signal Transduction Regulation Of Cell Shape Cell Migration Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Collateral Sprouting
Pathways		Rho GTPase cycle
Drugs
Diseases
GWAS		Asthma ( 29273806)	Coronary artery disease ( 29212778)
Interacting Genes		11 interacting genes: ADRB2 ITGA5 ITGB1 PTK2B PTPN18 RASA1 RHOA RND1 RND2 RND3 SMURF2	6 interacting genes: ARHGAP5 FNBP1 MEOX2 RACGAP1 UBXN11 VPS4A
Entrez ID		394	8153
HPRD ID		04060	03332
Ensembl ID		ENSG00000100852	ENSG00000108830
Uniprot IDs		Q13017	P52198
PDB IDs		2EE4 2EE5 5U4V
Enriched GO Terms of Interacting Partners?
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