LDHA and ABCC9

Data Source:
HPRD (in vivo)

		LDHA	ABCC9
Description		lactate dehydrogenase A	ATP binding cassette subfamily C member 9
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Membrane Extracellular Exosome	Plasma Membrane Inward Rectifying Potassium Channel Membrane Sarcomere Potassium Ion-transporting ATPase Complex
	Molecular Function	L-lactate Dehydrogenase Activity Protein Binding Kinase Binding Identical Protein Binding Cadherin Binding NAD Binding	Cation Channel Activity Potassium Channel Activity ATP Binding Sulfonylurea Receptor Activity ATP-activated Inward Rectifier Potassium Channel Activity Potassium Channel Regulator Activity ATPase Activity ATPase-coupled Cation Transmembrane Transporter Activity Transmembrane Transporter Activity ATPase-coupled Transmembrane Transporter Activity Ion Channel Binding
	Biological Process	Response To Hypoxia Lactate Metabolic Process Pyruvate Metabolic Process Glycolytic Process Response To Nutrient Response To Glucose NAD Metabolic Process Response To Drug Response To Hydrogen Peroxide Positive Regulation Of Apoptotic Process Response To Estrogen Post-embryonic Animal Organ Development Response To CAMP	Response To ATP Defense Response To Virus Transmembrane Transport Cardiac Conduction Potassium Ion Transmembrane Transport Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Transport Across Blood-brain Barrier Regulation Of Cardiac Conduction Potassium Ion Import Across Plasma Membrane
Pathways		Pyruvate metabolism	ATP sensitive Potassium channels ABC-family proteins mediated transport Ion homeostasis Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome
Drugs		NADH Etheno-NAD Nicotinamide Oxamic Acid Stiripentol Copper Artenimol	ATP Glyburide Nicorandil
Diseases			Atrial fibrillation
GWAS		Amyloid A serum levels ( 21124955)	Appendicular lean mass ( 33097823) Birth weight ( 27680694) Gout ( 22179738) Hippocampal sclerosis of aging ( 24770881) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Obesity-related traits ( 23251661) Offspring birth weight ( 31043758) Pulse pressure ( 30224653 30578418)
Interacting Genes		19 interacting genes: ABCC9 ACD DUX4 DYNLL1 FGFR1 HNRNPD HULC KCNJ11 LDHB MAPK10 NDRG1 PCNA POT1 PTPRF TERF1 TINF2 UPF2 XRN1 YWHAQ	6 interacting genes: EEF1G HSPB2 KCNJ11 KCNJ8 LDHA STX1A
Entrez ID		3939	10060
HPRD ID		01025	03258
Ensembl ID		ENSG00000134333	ENSG00000069431
Uniprot IDs		P00338 V9HWB9	A0A024RAV7 O60706
PDB IDs		1I10 4AJP 4JNK 4L4R 4L4S 4M49 4OJN 4OKN 4QO7 4QO8 4QSM 4QT0 4R68 4R69 4RLS 4ZVV 5IXS 5IXY 5W8H 5W8I 5W8J 5W8K 5W8L 5ZJD 5ZJE 5ZJF 6BAD 6BAG 6BAX 6BAZ 6BB0 6BB1 6BB2 6BB3 6MV8 6MVA 6Q0D 6Q13 6SBU 6SBV 6ZZR
Enriched GO Terms of Interacting Partners?
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