LBR and PRM1

Data Source:
HPRD (in vitro)

		LBR	PRM1
Description		lamin B receptor	protamine 1
Image
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Inner Membrane Integral Component Of Nuclear Inner Membrane Cytoplasm Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Nuclear Membrane	Nucleosome Nucleoplasm Cytosol
	Molecular Function	DNA Binding RNA Binding Protein Binding Lamin Binding Oxidoreductase Activity, Acting On The CH-CH Group Of Donors Delta14-sterol Reductase Activity Chromo Shadow Domain Binding NADPH Binding	DNA Binding Protein Binding
	Biological Process	Cholesterol Biosynthetic Process Sterol Biosynthetic Process Neutrophil Differentiation	DNA Packaging Multicellular Organism Development Spermatogenesis Cell Differentiation Chromosome Condensation
Pathways		Cholesterol biosynthesis Initiation of Nuclear Envelope (NE) Reformation Regulation of MECP2 expression and activity
Drugs
Diseases		HEM skeletal dysplasia; Greenberg dysplasia Pelger-Huet anomaly
GWAS		Delirium ( 29631748) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494)	Asthma ( 31959851) Bulimia nervosa ( 23568457) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Multiple sclerosis ( 31604244 22190364) Multiple sclerosis and type 2 diabetes (pleiotropy) ( 26920376) Obesity-related traits ( 23251661) Primary biliary cirrhosis ( 22961000)
Interacting Genes		12 interacting genes: AKAP8L CBX3 CBX5 CD81 FNBP4 H4C14 LMNB1 MECP2 PRM1 SRPK1 SRPK2 YWHAG	3 interacting genes: CLK2 LBR SRPK1
Entrez ID		3930	5619
HPRD ID		02488	01688
Ensembl ID		ENSG00000143815	ENSG00000175646
Uniprot IDs		Q14739	P04553 Q3MN80
PDB IDs		2DIG	2AWR
Enriched GO Terms of Interacting Partners?
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