RHOG and ELMOD2

Data Source:
BioGRID (pull down, affinity chromatography technology)

		RHOG	ELMOD2
Description		ras homolog family member G	ELMO domain containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Cell Cortex Secretory Granule Membrane Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle Extracellular Exosome	Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding Protein Kinase Binding	GTPase Activator Activity
	Biological Process	Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Rho Protein Signal Transduction Motor Neuron Axon Guidance Positive Regulation Of Cell Population Proliferation Regulation Of Cell Shape Rac Protein Signal Transduction Cell Projection Assembly Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Neutrophil Degranulation Engulfment Of Apoptotic Cell Positive Regulation Of Transcription, DNA-templated Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Protein Kinase B Signaling Cell Chemotaxis Activation Of GTPase Activity Regulation Of Ruffle Assembly Regulation Of Neutrophil Migration Positive Regulation Of Protein Localization To Plasma Membrane	Positive Regulation Of GTPase Activity Regulation Of Defense Response To Virus Defense Response To Virus
Pathways		GPVI-mediated activation cascade PIP3 activates AKT signaling Rho GTPase cycle Constitutive Signaling by Aberrant PI3K in Cancer RHO GTPases activate KTN1 Neutrophil degranulation PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Drugs
Diseases
GWAS		Lymphocyte percentage of white cells ( 32888494) Malaria ( 31844061) Plateletcrit ( 32888494)	Malaria ( 31844061) Rapid automised naming of letters ( 30741946) Select biomarker traits ( 17903293)
Interacting Genes		21 interacting genes: ARHGDIA ARHGDIG CCR2 DOCK1 ECT2 ELMO1 ELMO2 ELMOD2 ERCC6 IQGAP2 KTN1 MAP3K11 MCF2 MCF2L PLD1 SMAD1 SMAD4 TGFBR1 VAV1 VAV2 VAV3	2 interacting genes: HOXC4 RHOG
Entrez ID		391	255520
HPRD ID		01537	13267
Ensembl ID		ENSG00000177105	ENSG00000179387
Uniprot IDs		P84095 Q6ICQ8	Q8IZ81
PDB IDs		6UKA
Enriched GO Terms of Interacting Partners?
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