SMIM1 and RELL2

Data Source:
BioGRID (two hybrid)

		SMIM1	RELL2
Description		small integral membrane protein 1 (Vel blood group)	RELT like 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Integral Component Of Membrane	Basement Membrane Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Protein Homodimerization Activity	Protein Binding Collagen Binding
	Biological Process		Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of P38MAPK Cascade
Pathways
Drugs
Diseases
GWAS		Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494 27863252) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494 27863252) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)	Refractive error ( 32231278)
Interacting Genes		56 interacting genes: ANKS6 AQP6 ASZ1 BCL2L13 BIK CD74 CISD2 COMT CREB3L1 CYB561 EBP ERGIC3 FAM174A FAM209A FAM210B FCER1G FFAR2 FNDC9 GJA8 GJB5 HACD2 HSD17B13 ICAM3 JAGN1 KIR2DL3 LHFPL5 LRP10 LRRC4C MFF MFSD6 MUC1 NAALAD2 NDUFAF2 PVR REEP4 RELL2 RETREG3 SAR1A SCN3B SDC3 SIGLEC7 SLC10A6 SLC18A1 SLC26A11 STING1 STX1A TM4SF19 TMEM154 TMEM31 TMEM45B TMEM51 TMEM52B TMEM86B TMPRSS2 TMX2 ZDHHC15	21 interacting genes: ANKRD46 ASPH CDIPT CLDND2 COL4A5 FAM3C LPAR3 MIP NSG1 OXSR1 PLP1 RELL1 RTP2 SEC22B SLC30A8 SLC35A1 SMIM1 TFRC TSPAN33 TSPO2 ZFPL1
Entrez ID		388588	285613
HPRD ID			12830
Ensembl ID		ENSG00000235169	ENSG00000164620
Uniprot IDs		B2RUZ4 M4WDD3	Q8NC24
PDB IDs
Enriched GO Terms of Interacting Partners?
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