KRTAP10-1 and NR1D2

Data Source:
BioGRID (two hybrid)

		KRTAP10-1	NR1D2
Description		keratin associated protein 10-1	nuclear receptor subfamily 1 group D member 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament	Chromatin Nucleus Nucleoplasm Cytoplasm
	Molecular Function		RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Nuclear Receptor Activity Protein Binding Zinc Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Keratinization	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Hormone-mediated Signaling Pathway Regulation Of Lipid Metabolic Process Cell Differentiation Intracellular Receptor Signaling Pathway Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Circadian Behavior Regulation Of Inflammatory Response Negative Regulation Of Inflammatory Response Lipid Homeostasis Energy Homeostasis Regulation Of Skeletal Muscle Cell Differentiation
Pathways		Keratinization	Nuclear Receptor transcription pathway
Drugs			SR-9009 SR-9011
Diseases
GWAS			Acne (severe) ( 24927181) Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Asthma ( 29273806) Cognitive ability ( 29186694) Extremely high intelligence ( 29520040) General cognitive ability ( 29844566) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Metabolite levels ( 23823483) Parkinson's disease progression (cognitive) ( 33111402) Refractive error ( 32231278)
Interacting Genes		138 interacting genes: ADAMTSL4 AEN AMMECR1 ATP23 AVPI1 BAHD1 BCL6B C17orf50 C22orf39 CAMK1G CARD9 CATSPER1 CBX2 CHIC2 CHRD CLPP CRCT1 CREB5 CTSZ CXCL16 CYSRT1 DAAM2 DEFB112 DHX57 DKK1 DOCK2 ECE1 FAM76B FBXO34 FCHO1 FUCA2 GLRX3 HOXA1 HOXA9 HPCAL1 HSD3B7 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-8 KRTAP12-1 KRTAP13-3 KRTAP2-3 KRTAP2-4 KRTAP21-2 KRTAP26-1 KRTAP3-2 KRTAP3-3 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP5-1 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-4 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2C LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LINGO1 MAPKBP1 MEOX2 MOBP MRPL12 NBPF19 NECTIN2 NKD1 NLK NOTCH2NLA NPDC1 NR1D2 NR4A1 NR4A3 NUFIP2 OTX1 PID1 PIN1 PLLP POM121L8P POU4F2 PPARA PRKAG1 PRM2 PRPF31 RNF8 RSPO2 SH3GLB2 SHFL SLC23A1 SLC6A20 SMCP SPATA24 SPATA3 SPATA8 SPRY1 SPRY2 TNP2 TRIM42 TSPAN4 TULP3 WT1 ZBTB24 ZNF101 ZNF124 ZNF138 ZNF264 ZNF286A ZNF329 ZNF417 ZNF433 ZNF438 ZNF439 ZNF440 ZNF559 ZNF572 ZNF581 ZNF587 ZNF625 ZNF664 ZNF768 ZNF785 ZSCAN12 ZSCAN26	53 interacting genes: CRY1 CSNK1E CSNK2A2 CUL1 CYSRT1 DELEC1 EFEMP2 GTF2B HDAC1 HOXA1 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-3 KRTAP3-2 KRTAP3-3 KRTAP4-2 KRTAP5-6 KRTAP6-2 KRTAP9-2 KRTAP9-3 KRTAP9-8 LGALS8 MEOX2 MID2 MYLIP MYO15B NBPF19 NCOA5 NCOR1 NOTCH2NLA NR1D1 PCSK5 PRMT6 PROP1 RBPMS RGN RORC SIN3B TAF6 TAF9 TBC1D21 TENT5B TRIM27 TRIM55 TRIM63 TRIP6 UBE2I ZNF587
Entrez ID		386677	9975
HPRD ID		11184	03809
Ensembl ID		ENSG00000215455	ENSG00000174738
Uniprot IDs		P60331	B4DXD3 F1D8P2 Q14995
PDB IDs			2V0V 2V7C 3CQV 4N73
Enriched GO Terms of Interacting Partners?
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