KRTAP10-7 and GLP1R

Data Source:
BioGRID (two hybrid)

		KRTAP10-7	GLP1R
Description		keratin associated protein 10-7	glucagon like peptide 1 receptor
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Transmembrane Signaling Receptor Activity Glucagon Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Peptide Hormone Binding Glucagon-like Peptide 1 Receptor Activity
	Biological Process	Keratinization	Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Positive Regulation Of Cytosolic Calcium Ion Concentration CAMP-mediated Signaling Positive Regulation Of Blood Pressure Regulation Of Insulin Secretion Cellular Response To Glucagon Stimulus
Pathways		Keratinization	Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Glucagon-like Peptide-1 (GLP1) regulates insulin secretion G alpha (s) signalling events Glucagon-type ligand receptors ADORA2B mediated anti-inflammatory cytokines production
Drugs			Glucagon Exenatide Liraglutide Albiglutide Dulaglutide Lixisenatide Semaglutide
Diseases
GWAS			Blood sugar levels ( 29403010) Fasting blood glucose ( 25631608) Fasting blood glucose adjusted for BMI ( 25625282) Type 2 diabetes ( 32499647)
Interacting Genes		282 interacting genes: AEN ALDH3B1 ANKRD36BP1 AP1M1 APP AQP1 AVPI1 B4GALT7 BAHD1 BCL6B BMP7 BRME1 BUD31 BYSL C8orf33 CARHSP1 CATIP CBX2 CCDC185 CCDC26 CCNG1 CDCA7L CHIC2 CHRD CHRNG CLK1 CLK4 CNNM3 COL8A1 CRCT1 CREB5 CRY2 CSNK1G1 CSNK1G2 CTNNBIP1 CTRC CXCL16 CYSRT1 DAAM2 DERL2 DHX57 DMRT3 DOCK2 E2F6 E4F1 EHHADH FADS6 FAM124B FAM161A FAM27E3 FAM74A4 FAM76B FARS2 GABARAPL1 GABARAPL2 GEM GLIDR GLP1R GNE GOLGA8EP GRN GSTP1 GUCD1 HBZ HCK HHEX HOXA1 HOXC8 HPCAL1 HSBP1 HSD3B7 IGSF8 ING5 INPP5D IQUB ITGB4 ITGB5 KLHL38 KRT20 KRT83 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-3 KRTAP26-1 KRTAP4-2 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1D LCE1F LCE2A LCE2B LCE2C LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LIMS2 LINC00242 LMNA LMO2 LRCH4 MAPKBP1 MCM5 MCRS1 MOBP MRGBP MXD3 MXI1 MYPOP NAA10 NAXD NECTIN2 NECTIN3 NKD1 NOL12 NOTCH2NLA NPBWR2 NPDC1 NTAQ1 NUBP2 NUDCD3 NUFIP2 OTX1 P2RY6 PCED1A PCSK5 PDE9A PDIA5 PDLIM5 PFKL PGAP6 PHLDA1 PIN1 POLL POM121L8P PPARD PRKAB2 PRM2 PRR13 PRR35 PTGDS PTGER3 PTPMT1 PVR R3HDM2 RNF175 RPF1 RPL11 RPL36AL RPS28 RPUSD3 RSPO2 RTN4RL1 RWDD2B SCNM1 SDCBP SHFL SLC23A1 SLC25A48 SLC6A20 SMCO4 SMCP SPACA9 SPATA24 SPATA3 SPATA8 SPG7 SPRY1 SSX2IP STAT3 STK16 SUV39H1 TAPBPL TCEA2 TCEANC TEDC2 TFAP2D THAP1 THAP6 TLE5 TMA16 TNP2 TNS2 TOR1A TREX1 TRIM42 TTPA TULP3 TXNDC5 TYRO3 UCP2 UXT VASN VGLL3 VTI1B WNT11 WT1 ZBTB24 ZBTB38 ZBTB48 ZBTB9 ZFP41 ZFYVE26 ZIM2 ZNF101 ZNF124 ZNF133 ZNF138 ZNF155 ZNF165 ZNF169 ZNF175 ZNF180 ZNF2 ZNF20 ZNF223 ZNF250 ZNF256 ZNF26 ZNF260 ZNF264 ZNF266 ZNF32 ZNF320 ZNF329 ZNF337 ZNF408 ZNF41 ZNF414 ZNF417 ZNF418 ZNF419 ZNF420 ZNF425 ZNF433 ZNF439 ZNF440 ZNF444 ZNF490 ZNF491 ZNF524 ZNF543 ZNF555 ZNF564 ZNF572 ZNF575 ZNF578 ZNF580 ZNF581 ZNF587 ZNF625 ZNF667 ZNF670 ZNF696 ZNF697 ZNF707 ZNF764 ZNF774 ZNF778 ZNF786 ZNF792 ZNF837 ZNF844 ZNF846 ZNHIT1 ZSCAN10 ZSCAN21 ZSCAN26	112 interacting genes: ACSF3 AGXT AIG1 APH1A ARFRP1 ASGR2 ATP13A1 ATP5MC3 ATP6AP2 C18orf32 C4orf3 CALM1 CAND2 CAV1 CCDC167 CD63 CD81 CELA3B CEND1 CFI CLDN7 CLIP4 CLPS CNIH4 COMT CYSRT1 CYSTM1 DAD1 DHRS7 EBP ELOVL1 EMC7 EMP2 ERP29 FGL1 FTL GABBR2 GCG GJB1 GNAS GP2 GPR108 GPR37 GPRASP1 GRINA HAMP HPN IER3 IFITM3 KHK KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP17-1 KRTAP5-9 LAPTM4A LINC00269 MFSD5 MRPL22 MT-ATP6 MT-ND4L MTCH2 MYL6 NBPF19 NOTCH2NLA NRGN NUCKS1 OCIAD2 OST4 P4HTM PAM PAQR6 PGRMC1 PIGG POMT2 PPIB PRSS2 PSMD8 RAB5B RAB5C RNF5 RTN3 RTN4 RTRAF SAA1 SCGB2A1 SEC11C SELENOK SERPINA1 SLC15A4 SLC37A4 SPTSSA STMN1 STMN3 STOML2 SVOP SYNGR3 SYNGR4 SYS1 TM4SF4 TMBIM6 TMCO3 TMEM147 TMEM176B TOMM6 TSPAN13 UGT1A9 VAPB ZNF99
Entrez ID		386675	2740
HPRD ID		11193	00677
Ensembl ID		ENSG00000272804	ENSG00000112164
Uniprot IDs		P60409	A0A142FHB8 P43220
PDB IDs			3C59 3C5T 3IOL 4ZGM 5E94 5NX2 5OTT 5OTU 5OTV 5OTW 5OTX 5VEW 5VEX 6B3J 6GB1 6ORV 6VCB 6X18 6X19 6X1A 7C2E
Enriched GO Terms of Interacting Partners?
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