KRT10 and SNAPIN

Data Source:
BioGRID (two hybrid)

		KRT10	SNAPIN
Description		keratin 10	SNAP associated protein
Image			No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Extracellular Space Nucleus Cytoplasm Cytosol Intermediate Filament Cell Surface Membrane Extracellular Exosome	Golgi Membrane Acrosomal Vesicle Manchette Lysosomal Membrane Synaptic Vesicle Secretory Granule Synaptic Vesicle Membrane BLOC-1 Complex Synapse Perinuclear Region Of Cytoplasm BORC Complex Axon Cytoplasm
	Molecular Function	Protein Binding Structural Constituent Of Skin Epidermis Protein Heterodimerization Activity	SNARE Binding Protein Binding
	Biological Process	Peptide Cross-linking Keratinocyte Differentiation Keratinization Positive Regulation Of Epidermis Development Protein Heterotetramerization Cornification	Intracellular Protein Transport Lysosome Organization Lysosomal Lumen Acidification Neurotransmitter Secretion Anterograde Axonal Transport Retrograde Axonal Transport Endosome To Lysosome Transport Negative Regulation Of Neuron Projection Development Viral Process Synaptic Vesicle Exocytosis Synaptic Vesicle Maturation Neuron Projection Development Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Lysosome Localization Melanosome Organization Cellular Protein-containing Complex Localization Regulation Of Protein Binding Synaptic Vesicle Transport Anterograde Synaptic Vesicle Transport Protein Maturation Terminal Button Organization Autophagosome Maturation Late Endosome To Lysosome Transport Positive Regulation Of Late Endosome To Lysosome Transport Regulation Of Synaptic Vesicle Exocytosis
Pathways		Keratinization Formation of the cornified envelope	Golgi Associated Vesicle Biogenesis
Drugs		Zinc Copper Zinc acetate
Diseases		Ichthyosis with confetti; Congenital reticular ichthyosiform erythroderma; Ichthyosis variegata Epidermolytic hyperkeratosis (EHK); Bullous congenital ichthyosiform erythroderma (BCIE)
GWAS		Glucose homeostasis traits ( 25524916)
Interacting Genes		8 interacting genes: AKT1 ESR1 EVPL GLE1 PRKCZ SIRPA SMAD3 SNAPIN	103 interacting genes: ABI2 ACTN2 ATG14 ATP1A1 BANP BFSP1 BFSP2 BIN1 BLOC1S1 BLOC1S2 BLOC1S4 BLOC1S5 BLOC1S6 BNIPL C20orf202 CCDC102B CDC42BPA CEP170 CMYA5 CSNK1D DDR1 DENND1C DES DNM2 DOCK9 DST DTNBP1 DYSF EBAG9 EEF1G ELP1 ENO3 ENTHD1 EXOC1 EXOC7 FAM114A1 FSD2 GPRASP1 HAP1 IKBIP IMMT INSYN1 KANK2 KAT5 KAT7 KIF5C KPNB1 KRT10 KRT15 KRT16 KRT17 KRT19 KRT20 KRT24 KRT26 KRT27 LAMA2 LAMC1 LMNB1 LRP12 MACF1 MAPK14 MET MTNR1A MYH14 MYH3 MYH7 NECAB2 NEDD9 NME7 NUP62CL PCYT1A PLAC9 PLEC PRKACA RABEP1 RABGEF1 RETREG1 RGS7 RNF13 SHBG SKA1 SMAD2 SMG1 SNAP23 SNAP25 SPAG5 SPP1 SPTB SPTBN1 ST7 TFIP11 TOMM70 TPM1 TPM2 TPM3 TPM4 TRIM63 TRPV1 TSG101 WASHC3 YWHAE YWHAZ
Entrez ID		3858	23557
HPRD ID		01021	06111
Ensembl ID		ENSG00000186395	ENSG00000143553
Uniprot IDs		P13645	O95295
PDB IDs		3ASW 4F1Z 4ZRY 6E2J 6EC0 6UUI
Enriched GO Terms of Interacting Partners?
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