KRT6A and KRT4

Data Source:
BioGRID (affinity chromatography technology)

		KRT6A	KRT4
Description		keratin 6A	keratin 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Membrane Keratin Filament Extracellular Exosome	Nucleus Cytosol Intermediate Filament Cell Surface Keratin Filament Intermediate Filament Cytoskeleton
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding	Protein Binding
	Biological Process	Negative Regulation Of Cytolysis By Symbiont Of Host Cells Morphogenesis Of An Epithelium Cytoskeleton Organization Positive Regulation Of Cell Population Proliferation Cell Differentiation Keratinization Wound Healing Defense Response To Gram-positive Bacterium Cytolysis By Host Of Symbiont Cells Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cornification Negative Regulation Of Entry Of Bacterium Into Host Cell	Cytoskeleton Organization Epithelial Cell Differentiation Keratinization Negative Regulation Of Epithelial Cell Proliferation Cornification
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs		Zinc Zinc acetate
Diseases		Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex	White sponge nevus
GWAS		Cutaneous squamous cell carcinoma ( 32041948)
Interacting Genes		38 interacting genes: BEX2 CCDC85B DSP GEM GOLGA2 HGS KDM1A KIFC3 KRT13 KRT15 KRT16 KRT17 KRT18 KRT19 KRT25 KRT26 KRT27 KRT28 KRT31 KRT34 KRT35 KRT36 KRT38 KRT40 LMNA MTUS2 NCALD NUP62 SGTA SMARCB1 TCHP TFIP11 TRIM23 TRIM54 TSGA10 TXLNB UBQLN2 WASHC3	21 interacting genes: C14orf119 CCDC57 CEP57 KRT13 KRT15 KRT16 KRT19 KRT24 KRT25 KRT27 KRT28 KRT31 KRT33B KRT35 KRT36 KRT37 KRT38 KRT40 PPP1R13B TRIM54 TUBGCP4
Entrez ID		3853	3851
HPRD ID		01011	00478
Ensembl ID		ENSG00000205420	ENSG00000170477
Uniprot IDs		A0A0S2Z428 P02538	P19013
PDB IDs		5KI0
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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