KHK and LHX9

Data Source:
BioGRID (two hybrid, two hybrid)

		KHK	LHX9
Description		ketohexokinase	LIM homeobox 9
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GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome	Chromatin Nucleus
	Molecular Function	Ketohexokinase Activity Protein Binding ATP Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Fructose Metabolic Process Response To Sucrose Response To Glucose Response To Fructose Response To Zinc Ion Response To Insulin Carbohydrate Phosphorylation Fructose Catabolic Process To Hydroxyacetone Phosphate And Glyceraldehyde-3-phosphate Regulation Of Glycogen Metabolic Process	Regulation Of Transcription By RNA Polymerase II Cell Population Proliferation Male Gonad Development Female Gonad Development Neuron Differentiation Gonad Morphogenesis Negative Regulation Of Transcription, DNA-templated Dorsal Spinal Cord Interneuron Anterior Axon Guidance
Pathways		Essential fructosuria Fructose catabolism	Regulation of expression of SLITs and ROBOs
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Self-reported risk-taking behaviour ( 30181555) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	General risk tolerance (MTAG) ( 30643258) Heel bone mineral density ( 30598549)
Interacting Genes		4 interacting genes: APPBP2 GLP1R LHX2 LHX9	9 interacting genes: CSNK2A1 CWF19L2 IGFN1 KHK LDB1 LDB2 SMAD2 SMURF1 UBTFL1
Entrez ID		3795	56956
HPRD ID		11774	07299
Ensembl ID		ENSG00000138030	ENSG00000143355
Uniprot IDs		A0A140VJM6 P50053	H0YL54 Q9NQ69
PDB IDs		2HLZ 2HQQ 2HW1 3B3L 3NBV 3NBW 3NC2 3NC9 3NCA 3Q92 3QA2 3QAI 3RO4 5WBM 5WBO 5WBP 5WBQ 5WBR 5WBZ 6W0N 6W0W 6W0X 6W0Y 6W0Z	2DMQ
Enriched GO Terms of Interacting Partners?
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