KCNN4 and SLC30A2

Data Source:
BioGRID (two hybrid)

		KCNN4	SLC30A2
Description		potassium calcium-activated channel subfamily N member 4	solute carrier family 30 member 2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Vesicle Neuron Projection Neuronal Cell Body	Cytoplasm Lysosomal Membrane Late Endosome Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Potassium Channel Activity Protein Binding Calmodulin Binding Calcium-activated Potassium Channel Activity Small Conductance Calcium-activated Potassium Channel Activity Protein Phosphatase Binding Intermediate Conductance Calcium-activated Potassium Channel Activity	Zinc Ion Transmembrane Transporter Activity Protein Binding Identical Protein Binding
	Biological Process	Immune System Process Ion Transport Potassium Ion Transport Calcium Ion Transport Cell Volume Homeostasis Defense Response Stabilization Of Membrane Potential Phospholipid Translocation Saliva Secretion Positive Regulation Of Protein Secretion Positive Regulation Of T Cell Receptor Signaling Pathway Potassium Ion Transmembrane Transport	Response To Zinc Ion Regulation Of Sequestering Of Zinc Ion Positive Regulation Of Sequestering Of Zinc Ion Zinc Ion Transmembrane Transport
Pathways		Ca2+ activated K+ channels	Zinc efflux and compartmentalization by the SLC30 family
Drugs		Clotrimazole Quinine Procaine Miconazole Halothane Trimebutine
Diseases
GWAS		Breast cancer ( 23535729) Granulocyte percentage of myeloid white cells ( 27863252) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Mean corpuscular hemoglobin concentration ( 29403010 32888494 27863252) Mean corpuscular volume ( 29403010 32888494 27863252) Mean platelet volume ( 32888494) Monocyte count ( 27863252) Monocyte percentage of white cells ( 32888494 27863252) Neutrophil percentage of white cells ( 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 32888494) Red blood cell count ( 32888494) Reticulocyte count ( 32888494) White blood cell count ( 32888494)
Interacting Genes		9 interacting genes: BIK CALM1 CNIH3 FXYD3 GPR152 PMP22 PRKAG1 SLC30A2 STX1B	66 interacting genes: ABHD16A ADAM33 AQP2 AQP6 ATP13A1 C5orf46 CCL4 CCL4L2 CD40 CD52 CD79A CD99L2 CPLX4 CREB3 CTSA CYB561D2 EBAG9 EMP3 EVI2B F11R FAM174A FDPS FFAR2 FXYD3 FXYD6 GALNT15 GJA5 GJB2 GJB5 GLB1 GOLT1A GPR161 GPR42 GPRC5D HGFAC KASH5 KCNN4 LMNA LTA LYVE1 MS4A13 NDUFAF1 NRM OPRM1 PCNX2 PLPPR1 PVR SEC22A SELL SERPING1 SLC10A6 SLC16A2 SLC18A1 SLC38A7 SLC39A2 SLC7A1 SLC7A8 TAS2R5 TM4SF18 TMEM107 TMEM52B TMEM60 TMEM86A TNFRSF12A TRARG1 YIPF2
Entrez ID		3783	7780
HPRD ID		04130	18057
Ensembl ID		ENSG00000104783	ENSG00000158014
Uniprot IDs		O15554	Q9BRI3
PDB IDs		6CNM 6CNN 6CNO 6D42
Enriched GO Terms of Interacting Partners?
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