KCNJ10 and KCNJ16

Data Source:
HPRD (in vitro)

		KCNJ10	KCNJ16
Description		potassium inwardly rectifying channel subfamily J member 10	potassium inwardly rectifying channel subfamily J member 16
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane Cell Body Astrocyte Projection Presynapse	Plasma Membrane Voltage-gated Potassium Channel Complex Basolateral Plasma Membrane
	Molecular Function	Inward Rectifier Potassium Channel Activity Protein Binding ATP Binding ATP-activated Inward Rectifier Potassium Channel Activity	Inward Rectifier Potassium Channel Activity
	Biological Process	Potassium Ion Transport Visual Perception Adult Walking Behavior Central Nervous System Myelination Regulation Of Ion Transmembrane Transport Regulation Of Long-term Neuronal Synaptic Plasticity Glutamate Reuptake Potassium Ion Homeostasis Regulation Of Resting Membrane Potential Potassium Ion Import Across Plasma Membrane	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane
Pathways		Activation of G protein gated Potassium channels Potassium transport channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	Activation of G protein gated Potassium channels Potassium transport channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs		Yohimbine Butamben
Diseases		Seizures-sensorineural deafness-ataxia-mental retardation-electrolyte imbalance (SESAME) ; SeSAME/EAST syndrome
GWAS			Birth weight ( 31043758) Body mass index ( 26426971) Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872) Metabolite levels ( 23823483) Palmitoleic acid (16:1n-7) levels ( 23362303) Periodontitis (DPAL) ( 24024966) Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328) Serum metabolite levels ( 25569235) Thyrotoxic hypokalemic periodic paralysis ( 22863731) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		8 interacting genes: APP DLG1 DLG4 IL16 KCNJ16 PATJ SIAH1 SNTA1	4 interacting genes: KCNJ10 KCNJ15 KCNJ2 NEDD4
Entrez ID		3766	3773
HPRD ID		03732	16146
Ensembl ID		ENSG00000177807	ENSG00000153822
Uniprot IDs		P78508	A8K434 K7EJR9 Q8N538 Q9NPI9
PDB IDs
Enriched GO Terms of Interacting Partners?
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