CATIP and HESX1

Data Source:
BioGRID (two hybrid)

		CATIP	HESX1
Description		ciliogenesis associated TTC17 interacting protein	HESX homeobox 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Actin Cytoskeleton	Chromatin Nucleus
	Molecular Function	Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Protein Binding Protein C-terminus Binding Protein N-terminus Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Actin Filament Polymerization Cilium Organization	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Brain Development Gonad Development Gene Expression Pituitary Gland Development Thyroid Gland Development Otic Vesicle Formation Multicellular Organism Growth Camera-type Eye Development Nose Development Regulation Of Embryonic Development Forebrain Morphogenesis Leukemia Inhibitory Factor Signaling Pathway Stem Cell Differentiation Canonical Wnt Signaling Pathway ERK1 And ERK2 Cascade
Pathways
Drugs
Diseases			Septo-optic dysplasia Pituitary Dwarfism (PD); Isolated growth hormone deficiency (IGHD); Short Stature and Pituitary Defects (SSPD); Insulin-like growth factor 1 deficiency (IGFD)
GWAS			Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Family history of Alzheimer's disease ( 30617256)
Interacting Genes		15 interacting genes: APP BRD9 CEP72 CTNNBL1 DDIT4L GOLGA6L9 HESX1 KRT31 KRT40 KRTAP1-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 MEDAG MTUS2	12 interacting genes: C1orf109 CATIP GUCD1 HOXC8 KDM1A NCOR1 NPAS2 PRMT6 PROP1 STAT3 TLE1 UBL5
Entrez ID		375307	8820
HPRD ID		11846	03482
Ensembl ID		ENSG00000158428	ENSG00000163666
Uniprot IDs		Q7Z7H3	A1LQR0 Q9UBX0
PDB IDs			2K40
Enriched GO Terms of Interacting Partners?
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