KCNA5 and TMEM107

Data Source:
BioGRID (two hybrid)

		KCNA5	TMEM107
Description		potassium voltage-gated channel subfamily A member 5	transmembrane protein 107
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Caveola Voltage-gated Potassium Channel Complex Cell Surface Intercalated Disc Integral Component Of Membrane Z Disc Potassium Channel Complex Membrane Raft Intracellular Canaliculus Perinuclear Region Of Cytoplasm	Integral Component Of Membrane Ciliary Transition Zone MKS Complex
	Molecular Function	Signaling Receptor Binding Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Outward Rectifier Potassium Channel Activity Protein Kinase Binding Alpha-actinin Binding Voltage-gated Potassium Channel Activity Involved In Bundle Of His Cell Action Potential Repolarization Voltage-gated Potassium Channel Activity Involved In Atrial Cardiac Muscle Cell Action Potential Repolarization Voltage-gated Potassium Channel Activity Involved In SA Node Cell Action Potential Repolarization Scaffold Protein Binding	Molecular_function Protein Binding
	Biological Process	Response To Hypoxia Potassium Ion Transport Notch Signaling Pathway Response To Mechanical Stimulus Response To Organic Substance Regulation Of Vasoconstriction Regulation Of Membrane Potential Response To Hydrogen Peroxide Regulation Of Potassium Ion Transport Regulation Of Insulin Secretion Protein Homooligomerization Negative Regulation Of Cytosolic Calcium Ion Concentration Potassium Ion Homeostasis Response To Hyperoxia Membrane Hyperpolarization Regulation Of Atrial Cardiac Muscle Cell Membrane Repolarization Potassium Ion Transmembrane Transport Atrial Cardiac Muscle Cell Action Potential Membrane Repolarization During Bundle Of His Cell Action Potential Membrane Repolarization During SA Node Cell Action Potential Regulation Of Heart Rate By Cardiac Conduction Potassium Ion Export Across Plasma Membrane Membrane Repolarization During Atrial Cardiac Muscle Cell Action Potential Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Myoblast Proliferation	Detection Of Nodal Flow Regulation Of Gene Expression Neural Tube Patterning Embryonic Digit Morphogenesis Roof Of Mouth Development Cilium Assembly Craniofacial Suture Morphogenesis Protein Localization To Ciliary Transition Zone Non-motile Cilium Assembly
Pathways		Voltage gated Potassium channels
Drugs		Enflurane Promethazine Miconazole Vernakalant Dalfampridine Isavuconazole
Diseases		Atrial fibrillation
GWAS		Longevity ( 30294719)	Diastolic blood pressure ( 30224653) Urinary potassium excretion ( 31409800)
Interacting Genes		11 interacting genes: ACTN2 DLG1 DLG4 ERBIN KCNA2 PTPRE SNTA1 SRC TMEM107 TNK2 UBE2I	44 interacting genes: AQP3 AQP6 BIK CCL21 CD40 CD79A CLN8 CLSTN3 EBAG9 ERGIC3 EVI2B FAM209A FAM210B FCER1G GJA5 GJA8 GPX8 KCNA5 KCNJ6 LHFPL5 LMNA MGST3 MS4A3 PDZK1IP1 PGRMC2 PIGP SAR1A SLC10A6 SLC30A2 SLC35C2 SLC39A2 SYT2 THAP4 TMEM106A TMEM139 TMEM167B TMEM234 TMEM237 TMEM31 TMEM51 TMEM52B TMEM80 TMEM86B VMA21
Entrez ID		3741	84314
HPRD ID		08888	14400
Ensembl ID		ENSG00000130037	ENSG00000179029
Uniprot IDs		P22460	Q6UX40
PDB IDs
Enriched GO Terms of Interacting Partners?
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