ANOS1 and SDC2

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		ANOS1	SDC2
Description		anosmin 1	syndecan 2
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Cell Surface Extracellular Matrix	Endoplasmic Reticulum Lumen Golgi Lumen Plasma Membrane Cell Surface Integral Component Of Membrane Lysosomal Lumen Collagen-containing Extracellular Matrix
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Extracellular Matrix Structural Constituent Protein Binding Heparin Binding	Protein Binding PDZ Domain Binding Identical Protein Binding
	Biological Process	Chemotaxis Cell Adhesion Axon Guidance Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Endopeptidase Activity Neuron Differentiation	Retinoid Metabolic Process Glycosaminoglycan Biosynthetic Process Glycosaminoglycan Catabolic Process Biological_process Cell Migration Post-translational Protein Modification Cellular Protein Metabolic Process Ephrin Receptor Signaling Pathway Dendrite Morphogenesis Regulation Of Dendrite Morphogenesis Leukocyte Migration
Pathways		FGFR1c ligand binding and activation Negative regulation of FGFR1 signaling	A tetrasaccharide linker sequence is required for GAG synthesis HS-GAG biosynthesis HS-GAG biosynthesis HS-GAG degradation Cell surface interactions at the vascular wall Syndecan interactions Syndecan interactions Defective B4GALT7 causes EDS, progeroid type Defective B3GAT3 causes JDSSDHD Defective EXT2 causes exostoses 2 Defective EXT1 causes exostoses 1, TRPS2 and CHDS Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) EPHB-mediated forward signaling Defective B3GALT6 causes EDSP2 and SEMDJL1 Post-translational protein phosphorylation Retinoid metabolism and transport
Drugs			Sargramostim
Diseases		Hypogonadotropic hypogonadism; Kallmann syndrome (KAL)
GWAS		Estimated glomerular filtration rate ( 31015462)	Post-traumatic stress disorder ( 26114229) Refractive error ( 32231278)
Interacting Genes		6 interacting genes: FGFR2 FGFR3 FN1 NCALD SDC2 UBQLN1	28 interacting genes: ANOS1 ASPH BAG6 CASK CSF2 CYP2C18 EPHB2 EZR FGF2 FN1 HGF ITGB4 LAMA3 NF1 PF4 PPP3CC PRKCA PRKCB PRKCG REG3A SDCBP SERPINA1 SERPINC1 SPARC TGFB1 TGFBR3 TNFSF13 TRAPPC4
Entrez ID		3730	6383
HPRD ID		02393	00803
Ensembl ID		ENSG00000011201	ENSG00000169439
Uniprot IDs		P23352	A0A024R9D1 E9PBI9 P34741
PDB IDs		1ZLG	6ITH
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?