JUNB and BATF

Data Source:
HPRD (in vitro, two hybrid)

		JUNB	BATF
Description		JunB proto-oncogene, AP-1 transcription factor subunit	basic leucine zipper ATF-like transcription factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleoplasm Transcription Regulator Complex Transcription Factor AP-1 Complex	Chromatin Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Vasculogenesis Osteoblast Differentiation Trophectodermal Cell Differentiation Regulation Of Transcription By RNA Polymerase II Cytokine-mediated Signaling Pathway Osteoclast Differentiation Osteoblast Proliferation Regulation Of Cell Population Proliferation Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Decidualization Regulation Of Cell Cycle Embryonic Process Involved In Female Pregnancy Labyrinthine Layer Blood Vessel Development Cellular Response To Calcium Ion	Cytokine Production Lymphoid Progenitor Cell Differentiation Regulation Of Transcription By RNA Polymerase II Cellular Response To DNA Damage Stimulus Cytokine-mediated Signaling Pathway DNA Damage Response, Signal Transduction By P53 Class Mediator Defense Response To Protozoan Myeloid Dendritic Cell Differentiation T-helper 2 Cell Differentiation Isotype Switching Positive Regulation Of Transcription By RNA Polymerase II Hematopoietic Stem Cell Differentiation T-helper 17 Cell Differentiation T-helper 17 Cell Lineage Commitment
Pathways		SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Interleukin-4 and Interleukin-13 signaling NGF-stimulated transcription NGF-stimulated transcription	Interleukin-4 and Interleukin-13 signaling
Drugs
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29083406) LDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Multiple sclerosis ( 31604244 24076602 21833088) Rheumatoid arthritis ( 20453842)
Interacting Genes		39 interacting genes: APLP2 ATF4 BATF BATF2 BCL6 BDNF BRCA1 DDIT3 DNMT3L EP300 ESR1 FOS FOSB FOSL1 FOSL2 HOXA7 ITCH JDP2 MAP2 MAPK14 MAPK6 MAPK8 MAPK9 NEU1 NFE2L1 NINL PKIA SAT1 SET SMAD3 SMAD4 SMURF1 TCERG1 TDG UBA6 UBE2I USP24 ZNF595 ZSWIM9	21 interacting genes: ATF2 ATF3 ATF4 BATF3 CEBPA CEBPE CEBPG COX8A DBP DDIT3 EPAS1 FOS GOPC IFI35 IRF4 JUN JUNB JUND KDM1A NFIL3 SNAPC5
Entrez ID		3726	10538
HPRD ID		01303	09820
Ensembl ID		ENSG00000171223	ENSG00000156127
Uniprot IDs		P17275 Q5U079	Q16520
PDB IDs
Enriched GO Terms of Interacting Partners?
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