ITGA6 and CD151

Data Source:
HPRD (in vivo)

		ITGA6	CD151
Description		integrin subunit alpha 6	CD151 molecule (Raph blood group)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Adherens Junction Focal Adhesion Cell Surface Filopodium Integrin Alpha6-beta4 Complex	Basement Membrane Cytosol Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Cell Surface Membrane
	Molecular Function	Protein Binding Insulin-like Growth Factor I Binding Neuregulin Binding Laminin Binding Protein-containing Complex Binding Cadherin Binding Metal Ion Binding	Integrin Binding Protein Binding
	Biological Process	Cell-substrate Junction Assembly Integrin-mediated Signaling Pathway Ectodermal Cell Differentiation Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of Neuron Projection Development Extracellular Matrix Organization Positive Regulation Of Cell Migration Hemidesmosome Assembly Cell-substrate Adhesion Nail Development Positive Regulation Of Phosphorylation Positive Regulation Of Apoptotic Process Positive Regulation Of GTPase Activity Skin Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Leukocyte Migration Cellular Response To Organic Cyclic Compound Cell-cell Adhesion Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Cell Adhesion Viral Process Cell Migration Positive Regulation Of Cell Migration Hemidesmosome Assembly T Cell Proliferation Wound Healing, Spreading Of Cells Positive Regulation Of Endocytosis
Pathways		Assembly of collagen fibrils and other multimeric structures Basigin interactions Integrin cell surface interactions Integrin cell surface interactions Laminin interactions Laminin interactions Syndecan interactions Type I hemidesmosome assembly	Assembly of collagen fibrils and other multimeric structures Type I hemidesmosome assembly
Drugs
Diseases		Epidermolysis bullosa, junctional, including: Epidermolysis bullosa, junctional, Herlitz type (JEB-H); Epidermolysis bullosa, junctional, non-Herlitz type (JEB-nH); Epidermolysis bullosa, junctional, with pyloric atresia (JEB-PA)	Nephropathy with pretibial epidermolysis bullosa and deafness
GWAS		Alzheimer's disease biomarkers ( 23419831) Blood protein levels ( 28240269) Diabetic kidney disease ( 26305897) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Food allergy ( 29030101) Metabolite levels ( 23823483) Peanut allergy ( 29030101) Prostate cancer ( 31562322 19767753)	Mean platelet volume ( 32888494 27863252) Platelet count ( 32888494)
Interacting Genes		22 interacting genes: ADAM9 APP BIN1 CALM1 CANX CD151 CD36 CD63 CD82 COL17A1 GIPC1 GRB2 ITGB1 ITGB4 LGALS3BP PCSK5 PLEC PRKCD PXN RABIF RPSA TSPAN4	12 interacting genes: ARL13B BCL7A GRAMD1C ITGA3 ITGA6 ITGB1 KLRC1 MMP7 PTGFRN RNF128 TMEM139 TSPAN18
Entrez ID		3655	977
HPRD ID		00945	03763
Ensembl ID		ENSG00000091409	ENSG00000177697
Uniprot IDs		P23229	A0A024RCB3 P48509 Q6ZNZ0
PDB IDs
Enriched GO Terms of Interacting Partners?
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