INHBA and FSTL3

Data Source:
HPRD (in vitro)

		INHBA	FSTL3
Description		inhibin subunit beta A	follistatin like 3
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Activin A Complex Inhibin A Complex Perinuclear Region Of Cytoplasm	Extracellular Region Extracellular Space Nucleus Nucleoplasm Endoplasmic Reticulum Lumen Golgi Apparatus Secretory Granule Neuron Projection Terminus
	Molecular Function	Cytokine Activity Hormone Activity Protein Binding Growth Factor Activity Peptide Hormone Binding Inhibin Binding Identical Protein Binding Protein-containing Complex Binding Type II Activin Receptor Binding	Fibronectin Binding Protein Binding Activin Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Ovarian Follicle Development Hair Follicle Development Hematopoietic Progenitor Cell Differentiation Regulation Of Transcription By RNA Polymerase II Defense Response Cell Cycle Arrest Cell Surface Receptor Signaling Pathway Cell-cell Signaling Nervous System Development Negative Regulation Of Cell Population Proliferation Male Gonad Development Response To Wounding Positive Regulation Of Gene Expression Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Striatal Medium Spiny Neuron Differentiation Cell Differentiation Erythrocyte Differentiation Negative Regulation Of Cell Growth Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Interferon-gamma Production Activin Receptor Signaling Pathway Endodermal Cell Differentiation Negative Regulation Of Phosphorylation Odontogenesis Response To Drug Hemoglobin Biosynthetic Process Progesterone Secretion Negative Regulation Of B Cell Differentiation Positive Regulation Of Erythrocyte Differentiation Negative Regulation Of Macrophage Differentiation Negative Regulation Of Cell Cycle Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Follicle-stimulating Hormone Secretion Positive Regulation Of Follicle-stimulating Hormone Secretion Negative Regulation Of Follicle-stimulating Hormone Secretion Mesodermal Cell Differentiation Roof Of Mouth Development Positive Regulation Of Ovulation SMAD Protein Signal Transduction Eyelid Development In Camera-type Eye Cellular Response To Follicle-stimulating Hormone Stimulus Cellular Response To Cholesterol GABAergic Neuron Differentiation Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand	Ossification Kidney Development Hematopoietic Progenitor Cell Differentiation Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Spermatogenesis Male Gonad Development Positive Regulation Of Cell-cell Adhesion Cell Differentiation Lung Development Adrenal Gland Development Regulation Of BMP Signaling Pathway Negative Regulation Of BMP Signaling Pathway Negative Regulation Of Activin Receptor Signaling Pathway Post-translational Protein Modification Cellular Protein Metabolic Process Negative Regulation Of Osteoclast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Metal Ion Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Pathways		Signaling by Activin Signaling by Activin Glycoprotein hormones Antagonism of Activin by Follistatin	Antagonism of Activin by Follistatin Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Asthma ( 29273806) Cortisol levels (saliva) ( 28843169) Menarche (age at onset) ( 27182965 21102462 25231870) Parent of origin effect on language impairment (paternal) ( 24571439) Pit-and-Fissure caries ( 23470693)	Nickel levels ( 26025379)
Interacting Genes		13 interacting genes: ACVR1 ACVR1B ACVR2A ACVR2B CHRDL2 ENG FST FSTL3 IGFBP7 INHA INHBB INHBC TGFBR3	5 interacting genes: ADAM12 FN1 INHBA MSTN SMAD4
Entrez ID		3624	10272
HPRD ID		00929	05632
Ensembl ID		ENSG00000122641	ENSG00000070404
Uniprot IDs		A4D1W7 P08476	A0A024R1Y8 O95633
PDB IDs		1NYS 1NYU 1S4Y 2ARP 2ARV 2B0U 2P6A 3B4V 4MID 5HLY 5HLZ	2KCX 3B4V 3SEK
Enriched GO Terms of Interacting Partners?
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