ILF3 and PPP1R12A

Data Source:
BioGRID (unspecified method, affinity chromatography technology)

		ILF3	PPP1R12A
Description		interleukin enhancer binding factor 3	protein phosphatase 1 regulatory subunit 12A
Image
GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Nucleolus Cytoplasm Mitochondrion Membrane Ribonucleoprotein Complex	Kinetochore Nucleoplasm Nucleolus Cytoplasm Centrosome Cytosol Plasma Membrane Focal Adhesion Actin Cytoskeleton Z Disc A Band Contractile Fiber PTW/PP1 Phosphatase Complex
	Molecular Function	DNA Binding RNA Binding Double-stranded RNA Binding Single-stranded RNA Binding Protein Binding MRNA 3'-UTR AU-rich Region Binding	Enzyme Inhibitor Activity Protein Binding Phosphatase Regulator Activity Protein Kinase Binding 14-3-3 Protein Binding
	Biological Process	Protein Phosphorylation Negative Regulation Of Translation Negative Regulation Of Viral Genome Replication Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Defense Response To Virus	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Protein Dephosphorylation Centrosome Cycle Signal Transduction Regulation Of Cell Adhesion Regulation Of Myosin-light-chain-phosphatase Activity Positive Regulation Of Myosin-light-chain-phosphatase Activity Cellular Response To Drug Negative Regulation Of Catalytic Activity Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleocytoplasmic Transport Regulation Of Establishment Of Endothelial Barrier
Pathways			Regulation of PLK1 Activity at G2/M Transition RHO GTPases activate PKNs RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Chronotype ( 30696823) Height ( 25282103 25429064) Ischemic stroke ( 29531354) Obesity-related traits ( 23251661) Psoriasis ( 25903422 25574825 23143594) Psoriasis vulgaris ( 26626624) Rheumatoid arthritis ( 30423114) Stroke ( 29531354) Systemic lupus erythematosus ( 28714469)	Platelet count ( 32888494) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Interacting Genes		38 interacting genes: DHX9 DUX4 EIF2AK2 EP300 ERBB2 ERG ESR1 FUS GDF9 HNRNPH2 IL7R KRTAP4-12 LNX1 MAGEA11 MDFI NDRG1 PLSCR1 PPP1R12A PRMT1 PRMT5 PTEN RBM5 RBPMS RNF113A SF1 SF3B4 SMN1 SNRPC TRIM55 TRIM63 TRIP6 UBC UBE2D2 VPS37C XAB2 XPO5 ZNF346 ZNF830	14 interacting genes: ATXN10 CDKN3 DMPK IL16 ILF3 ILK KDM1A MPRIP PRKG1 RHOA ROCK1 ROCK2 SETD7 YWHAG
Entrez ID		3609	4659
HPRD ID		04420	03606
Ensembl ID		ENSG00000129351	ENSG00000058272
Uniprot IDs		A0A024R7C7 Q12906	B2RAH5 O14974
PDB IDs		2L33 3P1X	2KJY 5HUZ
Enriched GO Terms of Interacting Partners?
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