IL11RA and IL11

Data Source:
HPRD (in vivo, in vitro)

		IL11RA	IL11
Description		interleukin 11 receptor subunit alpha	interleukin 11
Image
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Receptor Complex	Extracellular Region Extracellular Space Cytoplasm
	Molecular Function	Transmembrane Signaling Receptor Activity Cytokine Receptor Activity Interleukin-11 Receptor Activity Protein Binding Cytokine Binding Interleukin-11 Binding	Cytokine Activity Interleukin-11 Receptor Binding Protein Binding Growth Factor Activity
	Biological Process	Positive Regulation Of Cell Population Proliferation Cytokine-mediated Signaling Pathway Developmental Process Interleukin-11-mediated Signaling Pathway Head Development	Positive Regulation Of Cell Population Proliferation Cytokine-mediated Signaling Pathway B Cell Differentiation Megakaryocyte Differentiation Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of MAPK Cascade Fat Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Hormone Secretion Positive Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Complement-dependent Cytotoxicity Negative Regulation Of Endothelial Cell Apoptotic Process
Pathways		IL-6-type cytokine receptor ligand interactions	IL-6-type cytokine receptor ligand interactions
Drugs		Oprelvekin
Diseases
GWAS		Blood protein levels ( 29875488) CTACK levels ( 27989323)	Appendicular lean mass ( 33097823) Osteoarthritis (hip) ( 30374069) Response to antidepressants ( 20360315)
Interacting Genes		2 interacting genes: IL11 OLFM4	3 interacting genes: IL11RA MAGEA11 UBQLN2
Entrez ID		3590	3589
HPRD ID		02965	00980
Ensembl ID		ENSG00000137070	ENSG00000095752
Uniprot IDs		Q14626 Q5VZ79	A8K3F7 P20809
PDB IDs		6O4P	4MHL 6O4O
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?