LCE3B and ALPP

Data Source:
BioGRID (two hybrid)

		LCE3B	ALPP
Description		late cornified envelope 3B	alkaline phosphatase, placental
Image		No pdb structure
GO Annotations	Cellular Component		Plasma Membrane Cell Surface Integral Component Of Membrane Anchored Component Of Membrane
	Molecular Function	Protein Binding	Magnesium Ion Binding Alkaline Phosphatase Activity Protein Binding Zinc Ion Binding
	Biological Process	Keratinization Killing Of Cells Of Other Organism Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium	Dephosphorylation
Pathways		Formation of the cornified envelope	Intra-Golgi traffic
Drugs			Calcium METHYL-PHOSPHONIC ACID MONO-(4-NITRO-PHENYL) ESTER
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Psoriasis ( 23143594)	Blood protein levels ( 30072576) Height ( 19570815) Refractive error ( 32231278)
Interacting Genes		40 interacting genes: ALPP CYP21A2 CYSRT1 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1B LCE1C LCE1D LCE1E LCE1F LCE2C LCE3A RGS17 RNF4 SMCP TGFB1 UBE2I ZMYM5	42 interacting genes: ADAMTSL4 ALPG CRCT1 CREB5 CXCL5 CYSRT1 FBXO34 GEMIN4 GPLD1 GSC2 HOXA1 IGFBP6 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-8 KRTAP4-12 KRTAP5-9 LATS1 LCE1D LCE1E LCE1F LCE2C LCE3A LCE3B LCE3C LCE3D LCE3E LCE5A LELP1 MEOX2 NBPF19 NLGN3 NOTCH2NLA NR4A3 OTX1 PIGK POU4F2 RGS19 RGS20 SMCP TGM1
Entrez ID		353143	250
HPRD ID		13974	01379
Ensembl ID		ENSG00000187238	ENSG00000163283
Uniprot IDs		Q5TA77	B2R7C7 P05187
PDB IDs			1EW2 1ZEB 1ZED 1ZEF 2GLQ 3MK0 3MK1 3MK2
Enriched GO Terms of Interacting Partners?
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