LCE2A and VASN

Data Source:
BioGRID (two hybrid)

		LCE2A	VASN
Description		late cornified envelope 2A	vasorin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Extracellular Space Mitochondrion Lysosomal Membrane Plasma Membrane Cell Surface Integral Component Of Membrane Extracellular Matrix Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding Cadherin Binding Transforming Growth Factor Beta Binding
	Biological Process	Keratinization	Negative Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Hypoxia Cellular Response To Redox State
Pathways		Formation of the cornified envelope
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)	Erectile dysfunction ( 30583798) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		48 interacting genes: ADAMTSL4 CREB5 CYSRT1 ECM1 GUCD1 HOXA1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP2-3 KRTAP2-4 KRTAP21-2 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-6 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE2B LCE2C LCE3A MEOX2 OTX1 PLA2G10 RGS17 RGS20 SPRY1 SUMO1P1 TRIM42 VASN	53 interacting genes: ADAMTSL4 AQP3 CIB4 CYSRT1 GRN GUCD1 HOXA1 KRT31 KRTAP1-1 KRTAP1-3 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP11-1 KRTAP12-2 KRTAP12-3 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP26-1 KRTAP3-1 KRTAP3-2 KRTAP4-1 KRTAP4-11 KRTAP4-2 KRTAP5-11 KRTAP6-3 KRTAP9-3 KRTAP9-8 LCE1C LCE2A LCE2C LCE2D LCE4A LNX1 MDFI MEOX2 MTUS2 NBPF19 NOTCH2NLA NR4A3 RGS17 RGS19 RGS20 RNF31 SMCP SSC4D TGFB1 TGFB2 TGFB3 TGM1 TRIP6 VWC2
Entrez ID		353139	114990
HPRD ID		13971	10587
Ensembl ID		ENSG00000187173	ENSG00000168140
Uniprot IDs		Q5TA79	Q6EMK4
PDB IDs
Enriched GO Terms of Interacting Partners?
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