LCE1C and PLAC8

Data Source:
BioGRID (two hybrid)

		LCE1C	PLAC8
Description		late cornified envelope 1C	placenta associated 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Extracellular Region Azurophil Granule Lumen
	Molecular Function	Protein Binding	Chromatin Binding
	Biological Process	Keratinization	Positive Regulation Of Cell Population Proliferation Response To Cold Negative Regulation Of Multicellular Organism Growth Defense Response To Bacterium Negative Regulation Of Apoptotic Process Neutrophil Degranulation Positive Regulation Of Transcription By RNA Polymerase II Brown Fat Cell Differentiation Positive Regulation Of Cold-induced Thermogenesis
Pathways		Formation of the cornified envelope	Neutrophil degranulation
Drugs
Diseases
GWAS		Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)	QRS interval (sulfonylurea treatment interaction) ( 27958378)
Interacting Genes		67 interacting genes: ADAMTSL4 CHIC2 CHRD CRCT1 CREB5 CYSRT1 EFEMP1 EFEMP2 FBLN1 GUCD1 HOXA1 KRTAP10-1 KRTAP10-5 KRTAP10-8 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP6-3 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1D LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE4A LCE5A MACO1 NECTIN2 NTAQ1 NTN4 NUTF2 ODF1 OIT3 OTX1 PLA2G10 PLAC8 PLSCR3 PLSCR4 POU4F2 PSMB1 SLC39A7 SPRED2 SPRY1 SPRY2 TGFB1 TRIM42 VASN VWC2 VWC2L	24 interacting genes: BAG4 C19orf54 COPS5 CYSRT1 FCHO1 KRTAP12-2 KRTAP19-1 KRTAP19-6 LCE1A LCE1C LCE2B LCE5A MEOX2 PLAGL2 PPP3CA RBPMS RHOXF2 TEX37 TRAF1 TRIP13 UBAP2 USP54 VAMP5 WWOX
Entrez ID		353133	51316
HPRD ID		13967	06335
Ensembl ID		ENSG00000197084	ENSG00000145287
Uniprot IDs		Q5T751	Q9NZF1 X2BQ60
PDB IDs
Enriched GO Terms of Interacting Partners?
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