LCE1A and NID2

Data Source:
BioGRID (two hybrid)

		LCE1A	NID2
Description		late cornified envelope 1A	nidogen 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Extracellular Region Basement Membrane Extracellular Space Plasma Membrane Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Protein Binding	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding Collagen Binding
	Biological Process	Cornification	Cell Adhesion Cell-matrix Adhesion Extracellular Matrix Organization Basement Membrane Organization
Pathways		Formation of the cornified envelope	Laminin interactions Laminin interactions
Drugs
Diseases
GWAS		Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)	Apolipoprotein A1 levels ( 32203549) Blood protein levels ( 29875488) Body mass index ( 28892062) Craniofacial microsomia ( 26853712) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) HDL cholesterol levels ( 32203549) Lung cancer (smoking interaction) ( 24658283) Pulmonary function ( 17903307) Triglyceride levels ( 32203549 29403010) Waist-to-hip ratio adjusted for body mass index ( 26785701)
Interacting Genes		69 interacting genes: ADAMTSL4 AQP1 CCN3 CFP CHIC2 CYSRT1 EFEMP2 FBLN1 FUCA2 GRN HOXA1 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP21-2 KRTAP3-2 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1B LCE1C LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE4A LCE5A MDFI MESD NBPF19 NID2 NOTCH2NLA PLA2G10 PLAC8 PLSCR2 PLSCR4 RGS17 RGS20 SLC39A7 SMCP SPRY1 SPRY2 SPRY3 TGFB1 TRIM42 TSPAN4 VWC2 VWC2L	24 interacting genes: ANKRD13D CCN3 COL13A1 COL1A1 COL4A1 ELN GNE HOXC8 HSPG2 KPRP KRTAP1-3 KRTAP10-3 KRTAP6-2 LAMC1 LCE1A MAML3 PITX1 PLSCR4 RBP3 SKIL TFG UNKL ZNF581 ZNF774
Entrez ID		353131	22795
HPRD ID		13966	05654
Ensembl ID		ENSG00000186844	ENSG00000087303
Uniprot IDs		Q5T7P2	Q14112
PDB IDs
Enriched GO Terms of Interacting Partners?
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