SLC35B2 and CYB5R3

Data Source:
BioGRID (two hybrid)

		SLC35B2	CYB5R3
Description		solute carrier family 35 member B2	cytochrome b5 reductase 3
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane Integral Component Of Membrane Integral Component Of Golgi Membrane Integral Component Of Endoplasmic Reticulum Membrane	Extracellular Region Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Hemoglobin Complex Membrane Azurophil Granule Lumen Nitric-oxide Synthase Complex
	Molecular Function	Protein Binding Transmembrane Transporter Activity 3'-phosphoadenosine 5'-phosphosulfate Transmembrane Transporter Activity	Cytochrome-b5 Reductase Activity, Acting On NAD(P)H Protein Binding AMP Binding ADP Binding Nitrite Reductase (NO-forming) Activity NAD Binding FAD Binding
	Biological Process	Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling 3'-phosphoadenosine 5'-phosphosulfate Transport 3'-phosphoadenosine 5'-phosphosulfate Biosynthetic Process 3'-phospho-5'-adenylyl Sulfate Transmembrane Transport	Cholesterol Biosynthetic Process Xenobiotic Metabolic Process Nitric Oxide Biosynthetic Process Blood Circulation L-ascorbic Acid Metabolic Process Neutrophil Degranulation
Pathways		Transport and synthesis of PAPS Transport of nucleotide sugars	Vitamin C (ascorbate) metabolism Phase I - Functionalization of compounds Neutrophil degranulation
Drugs			NADH Flavin adenine dinucleotide Copper
Diseases			Methemoglobinemia
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Initial pursuit acceleration ( 29064472)
Interacting Genes		14 interacting genes: AQP6 ASGR2 CD69 CLDN15 CREB3L1 CYB5R3 ERGIC3 GOLM1 LMNA RNF170 SHISAL1 TEX29 TMEM237 TMEM248	61 interacting genes: ADAM33 AGTRAP AIG1 ALG8 AQP6 ASGR1 BNIP2 CDIPT CERS4 CNIH1 COL8A2 CSGALNACT2 CYB5A CYCS ELOVL4 FAM210B FAM3C FAXDC2 FUNDC2 FXYD3 GAST GPR152 GRM2 HBG2 HSD17B13 LAPTM5 LRCH4 MFSD6 NINJ1 NRM NSG1 NXPE3 ORMDL2 PNLIPRP1 REEP4 SLC10A1 SLC10A6 SLC13A3 SLC22A2 SLC35A4 SLC35B2 SLC38A7 SPP1 STOM TMEM115 TMEM14B TMEM14C TMEM201 TMEM31 TMEM51 TMEM60 TMEM79 TNF TNFRSF10C UBIAD1 VAMP1 VAMP4 VAMP5 VMP1 WFDC2 ZDHHC15
Entrez ID		347734	1727
HPRD ID		11576	08942
Ensembl ID		ENSG00000157593	ENSG00000100243
Uniprot IDs		Q8TB61	P00387
PDB IDs			1M91 1UMK
Enriched GO Terms of Interacting Partners?
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