DGAT2L6 and SMG9

Data Source:
BioGRID (two hybrid)

		DGAT2L6	SMG9
Description		diacylglycerol O-acyltransferase 2 like 6	SMG9 nonsense mediated mRNA decay factor
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Cytosol
	Molecular Function	Protein Binding O-acyltransferase Activity	Protein Binding Identical Protein Binding
	Biological Process	Lipid Metabolic Process Monoacylglycerol Biosynthetic Process Acylglycerol Acyl-chain Remodeling	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Eye Development In Utero Embryonic Development Brain Development Heart Development
Pathways		Acyl chain remodeling of DAG and TAG	Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS			Lymphocyte counts ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 29403010) Mean corpuscular volume ( 29403010) Monocyte count ( 32888494)
Interacting Genes		45 interacting genes: ABHD4 ABHD5 ACSF2 AQP6 ARFIP2 BNIP2 CIAO2A DIABLO ECPAS FARS2 FBXL19 FCER1G GAD2 GPR152 HSD17B11 MCEMP1 MPP1 MTERF4 MYG1 NAPB NDRG4 PBX3 PGRMC2 PITPNC1 REEP4 RNF144A RNF5 RUSF1 SCAND1 SCN3B SLC10A1 SLC10A6 SMG9 SNX4 STAR THAP4 TMED8 TMEM143 TMEM14B TMEM255B TMEM31 TMX2 TTPA TUFM WIPI2	39 interacting genes: AGTRAP AK8 ARFIP2 CCDC57 CEP76 CMTM4 CTAG1A CTAG1B DGAT2L6 FNTB GOLGA2 GSG1 HSF2BP INCA1 KRT31 KRT34 KRTAP10-8 MTUS2 NFKBID PFDN5 PHF1 PLEKHG4 PNMA3 PPP2R3C PRKAR1B RASSF10 REL SLC17A9 SLC50A1 SYP TCF4 TRAF2 TRIM23 TRIM27 TRIP6 TSC1 TTC19 ZMYND12 ZNF655
Entrez ID		347516	56006
HPRD ID		13141	07800
Ensembl ID		ENSG00000184210	ENSG00000105771
Uniprot IDs		Q6ZPD8	A0A024R0Q0 Q9H0W8
PDB IDs			6L54 6SYT 6Z3R
Enriched GO Terms of Interacting Partners?
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