APOC4 and TIMMDC1

  • Data Source:
  • BioGRID (two hybrid)

APOC4

TIMMDC1

Description apolipoprotein C4 translocase of inner mitochondrial membrane domain containing 1
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (onset between ages 58 and 79) ( 30979435)
  • Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
  • Apolipoprotein A1 levels ( 32203549)
  • Blood protein levels ( 29875488 28240269)
  • Carotid intima media thickness (maximum) ( 31801372)
  • Carotid intima media thickness (mean) ( 31801372)
  • Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321)
  • Cerebrospinal AB1-42 levels in mild cognitive impairment ( 29274321)
  • Cerebrospinal AB1-42 levels in normal cognition ( 29274321)
  • Cerebrospinal fluid AB1-42 levels ( 29274321)
  • Cerebrospinal fluid p-tau levels ( 29274321)
  • Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321)
  • Cerebrospinal fluid t-tau levels ( 29274321)
  • Cerebrospinal fluid t-tau levels in mild cognitive impairment ( 29274321)
  • HDL cholesterol levels ( 32203549)
  • Hippocampal volume ( 29274321)
  • Hippocampal volume in Alzheimer's disease dementia ( 29274321)
  • LDL cholesterol ( 18802019 18193043 18193044 20864672 19060906)
  • Logical memory (delayed recall) ( 29274321)
  • Logical memory (immediate recall) ( 29274321)
  • Quantitative traits ( 19197348)
  • Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
  • Autoimmune thyroid disease ( 32581359)
  • Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761)
  • Medication use (thyroid preparations) ( 31015401)
  • Multiple sclerosis ( 31604244 24076602)
  • Primary biliary cholangitis ( 30643196)
  • Primary biliary cirrhosis ( 22961000)
  • Systemic lupus erythematosus ( 28714469)
  • Systemic sclerosis ( 31672989)
Interacting Genes 24 interacting genes: APOL2 BCL2L2 DIABLO GAD2 GSDMA IFI27 LETMD1 MAIP1 MICOS10 MICOS13 NFU1 PORCN RSAD2 SENP2 SNAP47 SYT16 TBC1D20 THBD TIMMDC1 TMEM14B TPRG1 UBQLN1 UBQLN2 VKORC1 70 interacting genes: AGR3 ANKRD46 APOC2 APOC4 APOL3 APP ARL6IP6 ATP6AP2 BCAP31 C14orf180 C3orf52 C4orf3 C5orf46 CCL4 CDS2 CMTM2 CREB3L1 CYP4F12 DCBLD2 DIABLO DRAM1 EPGN FAM20B FAM210B FATE1 FXYD3 GJB2 GPR151 GPR152 GPX8 HGS HSD17B13 IFNA2 KIR2DL4 LHFPL5 MARCHF5 MFSD14B MFSD5 NDUFB11 NINJ1 PEX5 PIGF PTPN1 PTPRN RNF24 SCAMP5 SCD SERF1A SERF1B SERP2 SLC35E4 SLC35F6 SMO ST6GAL2 STX12 STX6 TMEM144 TMEM14B TMEM176A TMEM199 TMEM203 TMEM239 TMEM31 TMEM54 TMEM65 TMEM86A TVP23B UNC93A YIF1A YIPF1
Entrez ID 346 51300
HPRD ID 02848 12817
Ensembl ID ENSG00000267467 ENSG00000113845
Uniprot IDs P55056 C9JU35 Q9NPL8
PDB IDs
Enriched GO Terms of Interacting Partners?
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