IFI35 and NMI

Data Source:
HPRD (two hybrid, in vivo)

		IFI35	NMI
Description		interferon induced protein 35	N-myc and STAT interactor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Cytoplasm Cytosol Membrane	Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Transcription Coregulator Activity Protein Binding Identical Protein Binding
	Biological Process	Macrophage Activation Involved In Immune Response Negative Regulation Of Cell Population Proliferation Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Innate Immune Response Positive Regulation Of Inflammatory Response Type I Interferon Signaling Pathway Negative Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of NIK/NF-kappaB Signaling	Macrophage Activation Involved In Immune Response Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Cell Population Proliferation Response To Virus Negative Regulation Of Interferon-alpha Production Negative Regulation Of Interferon-beta Production Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Innate Immune Response Negative Regulation Of Innate Immune Response Positive Regulation Of Inflammatory Response Interferon-gamma-mediated Signaling Pathway Negative Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Protein K48-linked Ubiquitination
Pathways		Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778)	Blood protein levels ( 28240269)
Interacting Genes		12 interacting genes: BATF BCAS2 CLEC4G CYTH3 EML2 FHL2 KDM1A MAPK1 NMI PLEKHO1 TRIM55 TRIM63	58 interacting genes: BRAT1 BRCA1 BRMS1 C1orf216 C9orf72 CDKN2A CDKN2D CNKSR3 CNOT7 COPS7B CYP2E1 EMILIN1 EXOSC5 GCSH GOLGA8EP HDDC3 HGS HHLA3 HOXC9 HSPA8 HSPH1 IFI35 KDM1A LCA5L LSM4 MAD2L1BP MCPH1 MORF4L1 MTMR6 MTMR9 MYC MYCN MYOM3 NECAP2 POMZP3 PSMA1 RYBP SCEL SFR1 SH3GLB2 SINHCAF SNAPC5 SOX10 STAT1 STAT3 STAT4 STAT5A STAT5B STAT6 THAP8 TRAF5 TRIM72 TRIP12 TUBA3C TUBA3E TXLNA TXLNB UBE2I
Entrez ID		3430	9111
HPRD ID		02844	04632
Ensembl ID		ENSG00000068079	ENSG00000123609
Uniprot IDs		P80217	Q13287
PDB IDs
Enriched GO Terms of Interacting Partners?
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