ANKRD33 and TRIM59

Data Source:
BioGRID (two hybrid)

		ANKRD33	TRIM59
Description		ankyrin repeat domain 33	tripartite motif containing 59
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Intraciliary Transport Particle B
	Molecular Function		Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Skeletal Muscle Cell Differentiation Negative Regulation Of Transcription Regulatory Region DNA Binding	Protein Ubiquitination Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response
Pathways
Drugs
Diseases
GWAS		Energy intake ( 30071075) Response to antipsychotic treatment in schizophrenia (reasoning) ( 21107309) Serum uric acid levels ( 30993211)	Alcohol use disorder (total score) ( 30336701) Bipolar disorder ( 31043756) Eosinophil percentage of white cells ( 32888494) Intrinsic epigenetic age acceleration ( 29374233) Malaria ( 31844061) Pulse pressure ( 30578418) Systolic blood pressure ( 30578418)
Interacting Genes		11 interacting genes: ANKRD11 BFSP2 GPSM3 HPCAL4 KLHL42 MBD3 SDCBP TLX3 TRIM59 UBQLN2 USHBP1	26 interacting genes: ANKRD33 BLZF1 CCDC33 CDK5 CLDN4 ECSIT EIF2B1 ESR1 ESR2 KRTAP13-3 MACROH2A1 MEI4 MRPL12 NECAB2 NRM PIN1 PLLP RASSF3 RHOU SEC22A SNAP47 UBE2J2 UBE2W VTI1B ZDHHC21 ZDHHC22
Entrez ID		341405	286827
HPRD ID		12465	15568
Ensembl ID		ENSG00000167612	ENSG00000213186
Uniprot IDs		Q0VAA8 Q5K617 Q7Z3H0	Q8IWR1
PDB IDs
Enriched GO Terms of Interacting Partners?
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