ENPP7 and LRRC73

Data Source:
BioGRID (two hybrid)

		ENPP7	LRRC73
Description		ectonucleotide pyrophosphatase/phosphodiesterase 7	leucine rich repeat containing 73
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Microvillus Membrane
	Molecular Function	Sphingomyelin Phosphodiesterase Activity Protein Binding Phosphoric Diester Hydrolase Activity Zinc Ion Binding	Protein Binding
	Biological Process	Sphingomyelin Metabolic Process Sphingomyelin Catabolic Process Glycosphingolipid Metabolic Process Negative Regulation Of DNA Replication Negative Regulation Of Cell Population Proliferation Lipid Digestion Positive Regulation Of Intestinal Cholesterol Absorption Fatty Acid Homeostasis Regulation Of Intestinal Lipid Absorption Positive Regulation Of Ceramide Biosynthetic Process Positive Regulation Of Sphingomyelin Catabolic Process
Pathways		Glycosphingolipid metabolism
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Diastolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		5 interacting genes: BACH2 GOLGA2 KRTAP5-9 LRRC73 MTUS2	8 interacting genes: ENPP7 GADD45GIP1 LNX1 NTAQ1 PICK1 RPP25 TSHZ3 ZNF574
Entrez ID		339221	221424
HPRD ID		10938	10167
Ensembl ID		ENSG00000182156	ENSG00000204052
Uniprot IDs		Q6UWV6	Q3B825 Q5JTD7
PDB IDs		5TCD 5UDY
Enriched GO Terms of Interacting Partners?
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