ICA1 and EXOC5

Data Source:
BioGRID (two hybrid)

		ICA1	EXOC5
Description		islet cell autoantigen 1	exocyst complex component 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Golgi Apparatus Cytosol Secretory Granule Membrane Synaptic Vesicle Membrane Intracellular Membrane-bounded Organelle	Exocyst Cytoplasm Cytosol Midbody
	Molecular Function	Protein Binding Protein Domain Specific Binding Membrane Curvature Sensor Activity	Protein Binding Small GTPase Binding
	Biological Process	Neurotransmitter Transport Regulation Of Insulin Secretion Regulation Of Transport	Exocytosis Post-Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Protein Transport
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Cognitive function ( 24684796) Intraocular pressure ( 23836780) Metabolite levels (Pyroglutamine) ( 23934736) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661) Systemic lupus erythematosus ( 28714469)	Alcohol consumption ( 23743675) Chronotype ( 30696823) Response to ranibizumab in age-related macular degeneration (exudative) ( 30054556)
Interacting Genes		6 interacting genes: CCDC28A EXOC5 ING5 MBD3 RAB2A RAB2B	43 interacting genes: ACTR3B ADCK1 ARF6 BARD1 BRMS1L C1orf216 CCDC102B CDH2 CRYBB1 DEUP1 DNAAF4 EDRF1 ENO2 EXOC6 EXOC6B FGA FRMD6 HDDC3 HGS ICA1 IFT57 KIFC3 KXD1 MAGEA3 MAGEA6 OAS1 PRKCG PSTPIP1 PTK6 PYCARD RAB14 RAB4A RAB4B RALA SOX10 SPACA9 TBX21 THOC1 TNPO2 TTC23L TXLNB TXNL4A USP2
Entrez ID		3382	10640
HPRD ID		00971	07258
Ensembl ID		ENSG00000003147	ENSG00000070367
Uniprot IDs		A0A024RA29 Q05084	O00471
PDB IDs
Enriched GO Terms of Interacting Partners?
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