Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
TNC and ITGA5
Data Source:
HPRD
(in vivo)
TNC
ITGA5
Description
tenascin C
integrin subunit alpha 5
Image
GO Annotations
Cellular Component
Extracellular Region
Basement Membrane
Interstitial Matrix
Extracellular Space
Endoplasmic Reticulum Lumen
Focal Adhesion
Membrane
Collagen-containing Extracellular Matrix
Perisynaptic Extracellular Matrix
Ruffle
Endoplasmic Reticulum
Golgi Apparatus
Plasma Membrane
Cell-cell Junction
Focal Adhesion
Integrin Complex
External Side Of Plasma Membrane
Cell Surface
Cytoplasmic Vesicle
Ruffle Membrane
Integrin Alpha5-beta1 Complex
Synapse
Alphav-beta3 Integrin-vitronectin Complex
Molecular Function
Extracellular Matrix Structural Constituent
Protein Binding
Syndecan Binding
Virus Receptor Activity
Epidermal Growth Factor Receptor Binding
Platelet-derived Growth Factor Receptor Binding
Integrin Binding
Protein Binding
Vascular Endothelial Growth Factor Receptor 2 Binding
Metal Ion Binding
Biological Process
Osteoblast Differentiation
Cell Adhesion
Negative Regulation Of Cell Adhesion
Neuromuscular Junction Development
Positive Regulation Of Cell Population Proliferation
Response To Wounding
Response To Mechanical Stimulus
Positive Regulation Of Gene Expression
Peripheral Nervous System Axon Regeneration
Extracellular Matrix Organization
Wound Healing
Odontogenesis Of Dentin-containing Tooth
Post-translational Protein Modification
Cellular Protein Metabolic Process
Response To Ethanol
Bud Outgrowth Involved In Lung Branching
Mesenchymal-epithelial Cell Signaling Involved In Prostate Gland Development
Prostate Gland Epithelium Morphogenesis
Cellular Response To Retinoic Acid
Cellular Response To Vitamin D
Response To Fibroblast Growth Factor
Cellular Response To Prostaglandin D Stimulus
Angiogenesis
Cell-substrate Junction Assembly
Cell Adhesion
Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules
Leukocyte Cell-cell Adhesion
Integrin-mediated Signaling Pathway
Female Pregnancy
Memory
Positive Regulation Of Cell-substrate Adhesion
CD40 Signaling Pathway
Extracellular Matrix Organization
Positive Regulation Of Cell Migration
Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Cell-substrate Adhesion
Cell Adhesion Mediated By Integrin
Cell-cell Adhesion Mediated By Integrin
Heterotypic Cell-cell Adhesion
Wound Healing, Spreading Of Epidermal Cells
Endodermal Cell Differentiation
Viral Entry Into Host Cell
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Leukocyte Migration
Positive Regulation Of Sprouting Angiogenesis
Negative Regulation Of Anoikis
Pathways
Integrin cell surface interactions
Syndecan interactions
ECM proteoglycans
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation
Elastic fibre formation
Fibronectin matrix formation
Cell surface interactions at the vascular wall
Integrin cell surface interactions
Integrin cell surface interactions
Signal transduction by L1
RUNX2 regulates genes involved in cell migration
Drugs
Resveratrol
Diseases
GWAS
Adult body size (
32376654
)
Blood protein levels (
29875488
28240269
)
Developmental language disorder (syntactic complexity) (
27016271
)
Inflammatory bowel disease (
23128233
)
Metabolite levels (
23823483
)
Mosquito bite size (
28199695
)
Osteoarthritis (hip) (
30374069
)
Response to bupropion and depression (
27622933
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Interacting Genes
6 interacting genes:
CNTN1
EGFR
FN1
ITGA5
NCAN
PTPRB
31 interacting genes:
ANGPT1
ANGPT2
ANGPTL3
ARHGAP5
AUP1
CD9
CLK1
COL18A1
COL1A1
EGFR
ERBB2
FGFR2
FLT4
FN1
GIPC1
GPR182
GRK6
ITGB1
ITGB3
ITGB5
L1CAM
LGALS3BP
NISCH
PECAM1
RABIF
SHARPIN
SPP1
STAMBP
TNC
UBAP1
VCL
Entrez ID
3371
3678
HPRD ID
01756
00627
Ensembl ID
ENSG00000041982
ENSG00000161638
Uniprot IDs
B4E1W8
J3QSU6
P24821
Q4LE33
B2R627
P08648
PDB IDs
1TEN
2RB8
2RBL
6BRB
6QNV
3VI3
3VI4
4WJK
4WK0
4WK2
4WK4
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?