APEX1 and UBR3

  • Data Source:
  • BioGRID (enzymatic study)

APEX1

UBR3

Description apurinic/apyrimidinic endodeoxyribonuclease 1 ubiquitin protein ligase E3 component n-recognin 3
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Longitudinal change in brain amyloid plaque burden ( 26268530)
  • Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
  • Urate levels in obese individuals ( 25811787)
Interacting Genes 43 interacting genes: ANP32A ANP32C APP CDC42 CSNK2A1 DCTN1 EP300 FBXO7 FEN1 GZMA GZMK HDAC1 HIF1A HMGA1 HMGA2 HMGB2 HNRNPL HOXC13 HSPA1A LINC01554 MCL1 MDM2 MUTYH NME1 NUDT3 NXF2 PCNA POLB POLR3D SET SRPK1 SRPK2 TCF21 TERF1 TERF2 TERF2IP TP53 TXN UBE2I UBR3 XRCC1 XRCC5 XRCC6 7 interacting genes: APEX1 DZIP3 MAGEC2 UBE2A UBE2B UBE2D2 UBE2H
Entrez ID 328 130507
HPRD ID 00136 15887
Ensembl ID ENSG00000100823 ENSG00000144357
Uniprot IDs P27695 Q5TZP7 Q6ZT12
PDB IDs 1BIX 1CQG 1CQH 1DE8 1DE9 1DEW 1E9N 1HD7 2ISI 2O3H 3U8U 4IEM 4LND 4QH9 4QHD 4QHE 5CFG 5DFF 5DFH 5DFI 5DFJ 5DG0 5WN0 5WN1 5WN2 5WN3 5WN4 5WN5 6BOQ 6BOR 6BOS 6BOT 6BOU 6BOV 6BOW 6MK3 6MKK 6MKM 6MKO 6P93 6P94 6W0Q 6W2P 6W3L 6W3N 6W3Q 6W3U 6W43 6W4I 6W4T
Enriched GO Terms of Interacting Partners?
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