HPCA and NUDC

Data Source:
BioGRID (affinity chromatography technology)

		HPCA	NUDC
Description		hippocalcin	nuclear distribution C, dynein complex regulator
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GO Annotations	Cellular Component	Cytoplasm Cytosol Extrinsic Component Of Membrane Axon Dendrite Membrane Neuronal Cell Body Membrane Dendrite Cytoplasm Perikaryon Dendritic Spine Head Glutamatergic Synapse	Nucleoplasm Cytoplasm Cytosol Microtubule Midbody Mitotic Spindle
	Molecular Function	Actin Binding Calcium Ion Binding Protein Binding Kinase Binding Identical Protein Binding	Protein Binding Cadherin Binding Unfolded Protein Binding
	Biological Process	Brain Development Calcium-mediated Signaling Negative Regulation Of Guanylate Cyclase Activity Activation Of Phospholipase D Activity Positive Regulation Of Adenylate Cyclase Activity Inner Ear Development Retina Development In Camera-type Eye Cellular Response To Electrical Stimulus Cellular Response To Calcium Ion Positive Regulation Of Protein Targeting To Membrane Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Regulation Of Voltage-gated Calcium Channel Activity Response To Ketamine Response To L-glutamate Cellular Response To Monosodium Glutamate Response To Aroclor 1254	Protein Folding Mitotic Spindle Organization Mitotic Metaphase Plate Congression Cell Division
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs			Phenethyl Isothiocyanate
Diseases
GWAS			Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Plateletcrit ( 27863252)
Interacting Genes		16 interacting genes: C1QTNF2 CKMT1A CKMT1B CREM DTX2 GATA5 IL36RN MLLT10 MYDGF NAIP NMT1 PRR35 SLC16A3 TEPSIN UQCRB VWC2	5 interacting genes: ACD PAFAH1B1 PLK1 POT1 TINF2
Entrez ID		3208	10726
HPRD ID		00811	10122
Ensembl ID		ENSG00000121905	ENSG00000090273
Uniprot IDs		P84074	Q9Y266
PDB IDs		5G4P 5G58 5M6C	3QOR
Enriched GO Terms of Interacting Partners?
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