HLA-DOA and HLA-DMA

Data Source:
HPRD (in vivo)

		HLA-DOA	HLA-DMA
Description		major histocompatibility complex, class II, DO alpha	major histocompatibility complex, class II, DM alpha
Image
GO Annotations	Cellular Component	Lysosomal Membrane Plasma Membrane Endosome Membrane Integral Component Of Membrane MHC Class II Protein Complex	Lysosomal Membrane Cell Surface Membrane Integral Component Of Membrane Late Endosome Membrane MHC Class II Protein Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding MHC Class II Protein Complex Binding MHC Class II Receptor Activity	Protein Binding MHC Class II Protein Complex Binding
	Biological Process	Adaptive Immune Response Negative Regulation Of Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of T Cell Differentiation	Adaptive Immune Response Peptide Antigen Assembly With MHC Class II Protein Complex Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Pathways		MHC class II antigen presentation
Drugs
Diseases			Allograft rejection
GWAS		Asthma ( 21804548 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Chronic hepatitis B infection ( 25802187) Lung cancer ( 28604730) Mortality in sepsis ( 27639821) Periodontitis (CDC/AAP) ( 24024966) Platelet count ( 22139419) Prostate cancer ( 29892016) Red wine liking ( 25758996) Wegener's granulomatosis ( 23740775) White wine liking ( 25758996)	Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848)
Interacting Genes		2 interacting genes: HLA-DMA REL	8 interacting genes: B3GAT1 CD74 CD82 HLA-DMB HLA-DOA HLA-DRA HLA-DRB1 U2AF2
Entrez ID		3111	3108
HPRD ID		00837	00830
Ensembl ID		ENSG00000204252	ENSG00000204257
Uniprot IDs		A0A1V0E3M7 A0A1V0E3N1 A0A1V0E3N3 A0A1V0E3N6 A0A1V0E3N7 A0A1V0E3P0 A0A1V0E3P1 A0A1V0E3P3 A0A1V0E3P6 A0A1V0E3P8 A0A1V0E3P9 A0A1V0E3Q1 A0A1V0E3Q2 A0A1V0E3Q3 A0A1V0E3Q4 A0A1V0E3Q5 A0A1V0E3Q6 A0A1V0E3Q7 A0A1V0E3Q8 A0A1V0E3R0 A0A1V0E3R3 A0A1V0E3R4 A0A1V0E3R6 A0A1V0E3R8 A0A1V0E3S0 A0A1V0E3S4 A0A1V0E3S6 A0A1V0E3S7 A0A1V0E3T1 P06340 X5CF87	Q31604 Q6ICR9
PDB IDs		4I0P	4I0P
Enriched GO Terms of Interacting Partners?
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