ANXA11 and ARSA

Data Source:
BioGRID (two hybrid)

		ANXA11	ARSA
Description		annexin A11	arylsulfatase A
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Nucleoplasm Cytoplasm Spindle Cytosol Membrane Midbody Melanosome Specific Granule Azurophil Granule Phagocytic Vesicle Collagen-containing Extracellular Matrix Extracellular Exosome	Extracellular Region Lysosome Endoplasmic Reticulum Lumen Azurophil Granule Lumen Lysosomal Lumen Extracellular Exosome
	Molecular Function	RNA Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding MHC Class II Protein Complex Binding S100 Protein Binding Calcium-dependent Protein Binding	Arylsulfatase Activity Cerebroside-sulfatase Activity Calcium Ion Binding Protein Binding Sulfuric Ester Hydrolase Activity
	Biological Process	Phagocytosis Cytokinetic Process Response To Calcium Ion	Glycosphingolipid Metabolic Process Neutrophil Degranulation
Pathways			Glycosphingolipid metabolism The activation of arylsulfatases Neutrophil degranulation
Drugs			4-Nitrocatechol sulfate 2-Amino-3-Hydroxy-3-Phosphonooxy-Propionic Acid
Diseases			Metachromatic leukodystrophy (MLD)
GWAS		Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Diabetic kidney disease ( 26305897) Sarcoidosis ( 22936702) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848)	Blood metabolite levels ( 24816252) Fibrinogen ( 23969696) Fibrinogen levels ( 28107422) QT interval (ambient particulate matter interaction) ( 28749367) Urinary metabolite levels in chronic kidney disease ( 31959995) vWF and FVIII levels ( 30586737)
Interacting Genes		18 interacting genes: ALG2 ARSA CDC42 CEP55 ENO2 EWSR1 FUBP1 HNRNPH3 KRTAP13-2 KRTAP6-2 NFKBID PDCD6 PLSCR1 S100A6 SRI TFG WWOX ZDHHC17	18 interacting genes: ANXA11 BMPR2 CAMK2B CCDC22 CETN2 CLEC4G CTSL EID2B FOXI1 GAL3ST1 PKN1 POU1F1 PPIC PROP1 RHOXF2 SNCA TRIP13 VENTX
Entrez ID		311	410
HPRD ID		03983	09617
Ensembl ID		ENSG00000122359	ENSG00000100299
Uniprot IDs		P50995 Q5T0G8	A0A0C4DFZ2 B4DVI5 P15289
PDB IDs			1AUK 1E1Z 1E2S 1E33 1E3C 1N2K 1N2L 2AIJ 2AIK 2HI8
Enriched GO Terms of Interacting Partners?
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