ZBTB48 and RGS2

Data Source:
BioGRID (two hybrid)

		ZBTB48	RGS2
Description		zinc finger and BTB domain containing 48	regulator of G protein signaling 2
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GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus	Nucleus Nucleolus Cytoplasm Mitochondrion Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Neuron Projection
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Double-stranded Telomeric DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Metal Ion Binding	G-protein Alpha-subunit Binding GTPase Activity GTPase Activator Activity Protein Binding Calmodulin Binding Beta-tubulin Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Transcription, DNA-templated	Response To Amphetamine Cell Cycle G Protein-coupled Receptor Signaling Pathway Spermatogenesis Brain Development Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Phospholipase Activity Negative Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Neuron Projection Development Negative Regulation Of Translation Ovulation Negative Regulation Of MAP Kinase Activity Positive Regulation Of GTPase Activity Negative Regulation Of CAMP-mediated Signaling Response To Ethanol Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Brown Fat Cell Differentiation Relaxation Of Cardiac Muscle Relaxation Of Vascular Associated Smooth Muscle Maternal Process Involved In Female Pregnancy Positive Regulation Of Cardiac Muscle Contraction Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of Adenylate Cyclase-inhibiting Adrenergic Receptor Signaling Pathway Involved In Heart Process Negative Regulation Of Glycine Import Across Plasma Membrane
Pathways			G alpha (q) signalling events
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654)	Coronary artery calcification ( 23870195) Response to quetiapine in schizophrenia ( 29503163)
Interacting Genes		33 interacting genes: C11orf58 CDK2AP2 CDKN1A CEP70 DVL2 DVL3 EP300 GPATCH2L ILK KRTAP1-1 KRTAP10-5 KRTAP10-7 L3MBTL2 LLCFC1 MCC NME7 PNRC2 RGS2 SPANXN2 THAP1 TNFRSF14 TRIM41 TSPYL2 UPF2 WDR5 ZBTB26 ZBTB6 ZBTB7A ZBTB8A ZBTB9 ZNF317 ZNF408 ZNF837	61 interacting genes: ADCY5 ADRA1A ADRB2 ARFGAP1 BBS10 CALM1 CEP126 CHD3 CIAO1 CLTA COMT COPB1 COPB2 CRMP1 CTSB DDR1 DUSP21 DYNLL1 EGFR EIF3L FZD5 GDE1 GIT1 GNA15 GNAI3 GNAQ GNAS HAUS5 HSPA8 IER3IP1 KLK8 LIG1 LRFN1 MARCHF6 METTL18 MON1A MTUS2 NINL NIPSNAP1 PPP1R9B PRKCA PRKCB PRKCG PRKCSH PRKG1 PRKN RAB2A RABAC1 RAP1B REEP5 RIN3 SCN5A TSPAN15 TUBB2B UBC VPS29 WDR74 XRCC6 ZBTB48 ZNF579 ZYX
Entrez ID		3104	5997
HPRD ID		01316	02917
Ensembl ID		ENSG00000204859	ENSG00000116741
Uniprot IDs		A8K291 B2R702 P10074	A0A024R939 P41220
PDB IDs		3B84 5YJ3	2AF0 2V4Z 4EKC 4EKD
Enriched GO Terms of Interacting Partners?
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