KCNIP1 and KCNIP2

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		KCNIP1	KCNIP2
Description		potassium voltage-gated channel interacting protein 1	potassium voltage-gated channel interacting protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Voltage-gated Potassium Channel Complex Dendrite Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane	Cytoplasm Plasma Membrane Voltage-gated Potassium Channel Complex Potassium Channel Complex Synapse
	Molecular Function	Voltage-gated Ion Channel Activity Potassium Channel Activity Calcium Ion Binding Protein Binding Potassium Channel Regulator Activity	A-type (transient Outward) Potassium Channel Activity Calcium Ion Binding Protein Binding Potassium Channel Regulator Activity Ion Channel Binding ER Retention Sequence Binding Protein N-terminus Binding Voltage-gated Potassium Channel Activity Involved In Cardiac Muscle Cell Action Potential Repolarization
	Biological Process	Cardiac Conduction Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport	Detection Of Calcium Ion Potassium Ion Transport Muscle Contraction Signal Transduction Chemical Synaptic Transmission Regulation Of Heart Contraction Clustering Of Voltage-gated Potassium Channels Cardiac Conduction Membrane Repolarization Membrane Repolarization During Cardiac Muscle Cell Action Potential Potassium Ion Export Across Plasma Membrane Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Potassium Ion Export Across Plasma Membrane Positive Regulation Of Voltage-gated Potassium Channel Activity
Pathways		Phase 1 - inactivation of fast Na+ channels	Phase 1 - inactivation of fast Na+ channels
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) California verbal learning test score ( 31596458) Liver transplant-free survival in primary sclerosing cholangitis (time to event) ( 28779025) Normalized brain volume ( 19010793) Placental abruption ( 29884306) Pre-treatment viral load in HIV-1 infection ( 31219150) Short-term memory (digit-span task) ( 30741946)	Raw vegetable consumption ( 32066663)
Interacting Genes		16 interacting genes: AMPD3 ASPH CIAO2A DAAM2 IL6ST KCND1 KCND2 KCND3 KCNIP2 LITAF NHLH2 NIF3L1 SOD3 SPP1 SPRED2 TBC1D25	5 interacting genes: GOLGA7 KCND2 KCND3 KCNIP1 SYCE1L
Entrez ID		30820	30819
HPRD ID		06879	06880
Ensembl ID		ENSG00000182132	ENSG00000120049
Uniprot IDs		Q9NZI2	A0A2R8Y6D7 B3KSZ5 Q9NS61
PDB IDs		1S1E 2I2R 2NZ0
Enriched GO Terms of Interacting Partners?
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