ANXA4 and GP2

Data Source:
HPRD (in vitro)

		ANXA4	GP2
Description		annexin A4	glycoprotein 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Cell Surface Vesicle Membrane Nuclear Membrane Perinuclear Region Of Cytoplasm Collagen-containing Extracellular Matrix Extracellular Exosome	Extracellular Region Extracellular Space Plasma Membrane Cell Surface Apical Plasma Membrane Anchored Component Of Membrane Extracellular Exosome
	Molecular Function	Phospholipase Inhibitor Activity Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Identical Protein Binding Calcium-dependent Protein Binding NF-kappaB Binding	Extracellular Matrix Structural Constituent
	Biological Process	Regulation Of Transcription By RNA Polymerase II Signal Transduction Notch Signaling Pathway Epithelial Cell Differentiation Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Interleukin-8 Production Negative Regulation Of Apoptotic Process Negative Regulation Of Catalytic Activity	Neutrophil Migration
Pathways			Post-translational modification: synthesis of GPI-anchored proteins
Drugs		Fluocinolone acetonide Copper
Diseases
GWAS		Atrial fibrillation ( 28416818 30061737) Palmitoleic acid (16:1n-7) levels ( 23362303)	Adult body size ( 32376654) Body mass index ( 22344219 24861553 28892062) Body size at age 10 ( 32376654) Chronic kidney disease ( 20383146) Diastolic blood pressure x smoking status (ever vs never) interaction (1df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Modified Stumvoll Insulin Sensitivity Index (BMI interaction) ( 27416945) Type 2 diabetes ( 32499647 30718926)
Interacting Genes		8 interacting genes: GP2 NMT2 PADI4 POT1 RHOU SMPD1 TINF2 UCHL5	6 interacting genes: AMY2A ANXA4 GLP1R JAGN1 SOX30 TSSK3
Entrez ID		307	2813
HPRD ID		00112	04279
Ensembl ID		ENSG00000196975	ENSG00000169347
Uniprot IDs		P09525 Q6LES2 Q6P452	B7Z1G2 P55259 Q68D34
PDB IDs		2ZOC
Enriched GO Terms of Interacting Partners?
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