HBZ and HBE1

Data Source:
BioGRID (two hybrid)

		HBZ	HBE1
Description		hemoglobin subunit zeta	hemoglobin subunit epsilon 1
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GO Annotations	Cellular Component	Hemoglobin Complex Haptoglobin-hemoglobin Complex Extracellular Exosome	Cytosol Hemoglobin Complex Haptoglobin-hemoglobin Complex Blood Microparticle
	Molecular Function	Peroxidase Activity Oxygen Carrier Activity Iron Ion Binding Protein Binding Oxygen Binding Heme Binding Haptoglobin Binding Organic Acid Binding	Peroxidase Activity Oxygen Carrier Activity Protein Binding Oxygen Binding Heme Binding Haptoglobin Binding Hemoglobin Alpha Binding Organic Acid Binding Protein-containing Complex Binding Metal Ion Binding
	Biological Process	Oxygen Transport Hydrogen Peroxide Catabolic Process Cellular Oxidant Detoxification	Blood Coagulation Response To Organic Cyclic Compound Oxygen Transport Hydrogen Peroxide Catabolic Process Cellular Oxidant Detoxification
Pathways			Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Body mass index ( 26426971) Early cardiac repolarization ( 31600170) Hemoglobin ( 32888494) Hemoglobin levels ( 26366553) Mean corpuscular hemoglobin ( 29403010 32888494 27863252) Mean corpuscular hemoglobin concentration ( 29403010) Mean corpuscular volume ( 29403010 27863252) Red blood cell count ( 29403010 32888494)	Beta thalassemia/hemoglobin E disease ( 20183929) Hematology traits ( 23263863) Hemoglobin ( 28548082) Hemoglobin levels ( 26366553) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Logical memory (delayed recall) in normal cognition ( 29274321) Logical memory (immediate recall) in normal cognition ( 29274321) Malaria ( 31844061) Mean corpuscular hemoglobin concentration ( 23263863 28453575) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494 27863252) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		29 interacting genes: APP CARD10 CCNDBP1 CYSRT1 DOCK8 FGFR3 GOLGA6L9 HBB HBD HBE1 HBM HBQ1 HNRNPD HNRNPK IKBKG KHDRBS2 KHDRBS3 KRT31 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 MTUS2 NBPF19 NOTCH2NLA NTAQ1 RBMY1A1 SP1 UPF2	4 interacting genes: HBA1 HBA2 HBQ1 HBZ
Entrez ID		3050	3046
HPRD ID		00794	00788
Ensembl ID		ENSG00000130656	ENSG00000213931
Uniprot IDs		P02008	D9YZU7 P02100
PDB IDs		1JEB 3W4U	1A9W
Enriched GO Terms of Interacting Partners?
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