GUCY2D and RGS9

Data Source:
HPRD (in vivo)

		GUCY2D	RGS9
Description		guanylate cyclase 2D, retinal	regulator of G protein signaling 9
Image			No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Nuclear Outer Membrane Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Photoreceptor Outer Segment Membrane Photoreceptor Disc Membrane	Nucleus Cytoplasm Plasma Membrane Postsynaptic Density Membrane Glutamatergic Synapse
	Molecular Function	Peptide Receptor Activity Guanylate Cyclase Activity Protein Kinase Activity Protein Binding ATP Binding GTP Binding Signaling Receptor Activity Protein Homodimerization Activity	GTPase Activity GTPase Activator Activity
	Biological Process	CGMP Biosynthetic Process Protein Phosphorylation Signal Transduction Receptor Guanylyl Cyclase Signaling Pathway Visual Perception Regulation Of Rhodopsin Mediated Signaling Pathway Intracellular Signal Transduction	Response To Amphetamine Protein Folding G Protein-coupled Receptor Signaling Pathway Dopamine Receptor Signaling Pathway Nervous System Development Visual Perception Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Response To Estradiol Intracellular Signal Transduction Positive Regulation Of GTPase Activity Positive Regulation Of NMDA Glutamate Receptor Activity Regulation Of Calcium Ion Export Across Plasma Membrane
Pathways		Inactivation, recovery and regulation of the phototransduction cascade	G alpha (i) signalling events G alpha (i) signalling events Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Drugs
Diseases		Leber congenital amaurosis (LCR) Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)	Bradyopsia
GWAS		Refractive error ( 32231278)	Adverse response to antithyroid drugs in Graves disease ( 30067105) Heel bone mineral density ( 30598549 28869591)
Interacting Genes		5 interacting genes: GUCA1A GUCA1B GUCA2B RGS9 S100B	5 interacting genes: ADRB2 GNAT1 GNB5 GUCY2D RGS9BP
Entrez ID		3000	8787
HPRD ID		02550	04962
Ensembl ID		ENSG00000132518	ENSG00000108370
Uniprot IDs		Q02846	A8K1G1 O75916
PDB IDs		1AWL
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?