PACSIN1 and MT-ATP8

Data Source:
BioGRID (two hybrid)

		PACSIN1	MT-ATP8
Description		protein kinase C and casein kinase substrate in neurons 1	ATP synthase F0 subunit 8
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Cytosol Cytoskeleton Plasma Membrane COPI-coated Vesicle Cytoplasmic Vesicle Membrane Ruffle Membrane Axon Terminus Synapse Perinuclear Region Of Cytoplasm Photoreceptor Ribbon Synapse Presynaptic Endocytic Zone	Mitochondrial Proton-transporting ATP Synthase Complex, Coupling Factor F(o) Mitochondrial Inner Membrane Mitochondrial Proton-transporting ATP Synthase Complex Integral Component Of Membrane
	Molecular Function	Protein Binding Phospholipid Binding Identical Protein Binding	Proton-transporting ATP Synthase Activity, Rotational Mechanism
	Biological Process	Cytoskeleton Organization Actin Filament Organization Regulation Of Endocytosis Negative Regulation Of Endocytosis Synaptic Vesicle Endocytosis Neuron Projection Morphogenesis Protein Localization To Membrane Protein Localization To Plasma Membrane Plasma Membrane Tubulation Positive Regulation Of Dendrite Development	ATP Biosynthetic Process Cristae Formation Mitochondrial ATP Synthesis Coupled Proton Transport
Pathways		Clathrin-mediated endocytosis	Formation of ATP by chemiosmotic coupling Cristae formation
Drugs
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 29273807 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Electrocardiographic traits ( 32602732) Free thyroxine concentration ( 30367059) High density lipoprotein cholesterol levels ( 30498476) Inflammatory bowel disease ( 27569725) Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes		25 interacting genes: ANKRD24 ARHGAP17 DNM1 EHBP1 FTH1 GAS7 HTT ITCH JADE2 KAT7 KHDRBS1 MAPT MT-ATP8 PACSIN2 PACSIN3 PLEKHF2 POT1 RTKN2 SOS1 SPTBN1 SYNJ1 TPM4 TRPV4 WASF2 WASL	4 interacting genes: GRB2 PACSIN1 RAPGEF2 WNK1
Entrez ID		29993	4509
HPRD ID		05936
Ensembl ID		ENSG00000124507	ENSG00000228253
Uniprot IDs		Q5TZC3 Q9BY11	A0A1X7RCP4 P03928 U5YV54
PDB IDs		3HAH 3HAI 3Q84 3QNI
Enriched GO Terms of Interacting Partners?
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