GYPC and RHBDD1

Data Source:
BioGRID (two hybrid)

		GYPC	RHBDD1
Description		glycophorin C (Gerbich blood group)	rhomboid domain containing 1
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Membrane Cortical Cytoskeleton	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane Mitochondrial Membrane Endoplasmic Reticulum Quality Control Compartment
	Molecular Function	Protein Binding	Serine-type Endopeptidase Activity Protein Binding
	Biological Process	Leukocyte Migration	Apoptotic Process Positive Regulation Of Protein Processing Membrane Protein Intracellular Domain Proteolysis Cellular Response To Unfolded Protein Cellular Response To UV ERAD Pathway Negative Regulation Of Apoptotic Process Post-translational Protein Modification Spermatid Differentiation Membrane Protein Proteolysis Involved In Retrograde Protein Transport, ER To Cytosol Regulation Of Male Germ Cell Proliferation
Pathways		Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Atrial fibrillation ( 30061737 29892015) Diastolic blood pressure ( 30224653) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Initial pursuit acceleration ( 29064472) Intelligence ( 22449649) Metabolite levels ( 23823483) Pelvic organ prolapse (moderate/severe) ( 26545240) Pyoderma gangrenosum in inflammatory bowel disease ( 24487271) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systolic blood pressure ( 31217584) Tea consumption ( 31046077)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Pulmonary function ( 17903307)
Interacting Genes		13 interacting genes: ABHD16A AQP6 EPB41 GPR42 MPP1 PDIA3 PLPPR2 RHBDD1 SHISAL1 SLC10A6 TMEM14B TMEM88 TSPAN15	18 interacting genes: CGRRF1 CMTM5 CREB3L1 CTSA DAPK1 FBXO25 GYPC LPCAT2 LRRK2 MFHAS1 NSDHL PLEKHB2 RNF5 SEC22B SLC66A2 TMEM42 TMEM86B TMIE
Entrez ID		2995	84236
HPRD ID		00193	13206
Ensembl ID		ENSG00000136732	ENSG00000144468
Uniprot IDs		P04921	Q8TEB9
PDB IDs		2EJY	5EPP
Enriched GO Terms of Interacting Partners?
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