GTF2A1 and TAF4B

Data Source:
BioGRID (pull down)

		GTF2A1	TAF4B
Description		general transcription factor IIA subunit 1	TATA-box binding protein associated factor 4b
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFIIA Complex Cytosol Transcription Preinitiation Complex	Fibrillar Center Nucleoplasm Transcription Factor TFIID Complex Cytoplasm
	Molecular Function	RNA Polymerase II Core Promoter Sequence-specific DNA Binding RNA Polymerase II Repressing Transcription Factor Binding DNA Binding Protein Binding Transcription Factor Binding RNA Polymerase II General Transcription Initiation Factor Activity TBP-class Protein Binding Protein Heterodimerization Activity	DNA Binding RNA Polymerase II General Transcription Initiation Factor Activity Protein Heterodimerization Activity NF-kappaB Binding
	Biological Process	Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter SnRNA Transcription By RNA Polymerase II	Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Spermatogenesis Oogenesis Regulation Of Signal Transduction By P53 Class Mediator
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance Estrogen-dependent gene expression	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Neutrophil count ( 32888494) Night sleep phenotypes ( 27126917) Thyroid stimulating hormone levels ( 32769997) White blood cell count ( 32888494)	Asthma-chronic obstructive pulmonary disease overlap syndrome ( 30657218) Red blood cell count ( 32888494) Rhegmatogenous retinal detachment ( 23585552) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		26 interacting genes: BCL3 BIRC7 CREB1 CSNK2A1 CSNK2A2 GTF2A2 GTF2E1 GTF2E2 GTF2F1 HMGB1 NCOA6 NFYA PRR20A PRR20B PRR20C PRR20D PRR20E PSMC6 SP4 TAF1 TAF4 TAF4B TASP1 TBP TBPL1 TRIP4	5 interacting genes: GTF2A1 H3-4 RELA TAF1 TAF12
Entrez ID		2957	6875
HPRD ID		02748	19270
Ensembl ID		ENSG00000165417	ENSG00000141384
Uniprot IDs		P52655	B4DYT3 J3KTH2 Q92750
PDB IDs		1NVP 5FUR 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 5M4S 6MZM 6O9L
Enriched GO Terms of Interacting Partners?
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