GSTP1 and KRT33B

Data Source:
BioGRID (two hybrid)

		GSTP1	KRT33B
Description		glutathione S-transferase pi 1	keratin 33B
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Cytoplasm Mitochondrion Cytosol Plasma Membrane Vesicle Secretory Granule Lumen Extracellular Exosome TRAF2-GSTP1 Complex Ficolin-1-rich Granule Lumen	Extracellular Space Cytosol Intermediate Filament Extracellular Exosome
	Molecular Function	Glutathione Transferase Activity Glutathione Peroxidase Activity Fatty Acid Binding Protein Binding Drug Binding JUN Kinase Binding Kinase Regulator Activity S-nitrosoglutathione Binding Dinitrosyl-iron Complex Binding Glutathione Binding Nitric Oxide Binding	Structural Molecule Activity Protein Binding
	Biological Process	Response To Reactive Oxygen Species Negative Regulation Of Acute Inflammatory Response Negative Regulation Of Protein Kinase Activity Prostaglandin Metabolic Process Glutathione Metabolic Process Xenobiotic Metabolic Process Central Nervous System Development Negative Regulation Of Biosynthetic Process Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Oligodendrocyte Development Animal Organ Regeneration Response To Estradiol Negative Regulation Of Interleukin-1 Beta Production Negative Regulation Of Tumor Necrosis Factor Production Cellular Response To Insulin Stimulus Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Superoxide Anion Generation Response To L-ascorbic Acid Cellular Response To Oxidative Stress Common Myeloid Progenitor Cell Proliferation Nitric Oxide Storage Negative Regulation Of Apoptotic Process Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Response To Amino Acid Neutrophil Degranulation Negative Regulation Of MAP Kinase Activity Negative Regulation Of MAPK Cascade Negative Regulation Of JUN Kinase Activity Linoleic Acid Metabolic Process Response To Ethanol Negative Regulation Of Fibroblast Proliferation Hepoxilin Biosynthetic Process Negative Regulation Of Nitric-oxide Synthase Biosynthetic Process Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Leukocyte Proliferation Cellular Response To Lipopolysaccharide Cellular Response To Epidermal Growth Factor Stimulus Cellular Response To Glucocorticoid Stimulus Cellular Response To Cell-matrix Adhesion Negative Regulation Of Monocyte Chemotactic Protein-1 Production Negative Regulation Of Smooth Muscle Cell Chemotaxis Cellular Oxidant Detoxification Glutathione Derivative Biosynthetic Process Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Aging Keratinization Hair Cycle Cornification
Pathways		Glutathione conjugation Detoxification of Reactive Oxygen Species Neutrophil degranulation	Keratinization Formation of the cornified envelope
Drugs		Glutathione Troglitazone Clozapine Etacrynic acid Clomipramine (9R,10R)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene S-Hydroxycysteine Cibacron Blue Glutathione sulfonic acid Glutathione disulfide Deoxycholic acid S-(4-nitrobenzyl)glutathione 2-(N-morpholino)ethanesulfonic acid S-Hexylglutathione Carbocisteine Canfosfamide Ezatiostat Exisulind S-NONYL-CYSTEINE S-(4-BROMOBENZYL)CYSTEINE Curcumin Dinitrochlorobenzene Hypericin Curcumin sulfate
Diseases		Prostate cancer
GWAS		Blood protein levels ( 29875488) Refractive error ( 32231278)
Interacting Genes		35 interacting genes: ADAMTSL4 APPBP2 CARD10 CYSRT1 FANCC FHL5 HOXA1 KRT31 KRT33B KRT34 KRT83 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP3-1 KRTAP3-3 KRTAP6-2 LRP2BP MAPK8 MLH1 MTUS2 NBPF19 NOTCH2NLA PNO1 PRDX6 PTN SCAF1 SH3GLB1 SUMO4 TGM1 TGM2 TRAF2 ZNF655	56 interacting genes: ABI2 AIMP2 AQP1 ARFIP1 ATG9A C1orf216 CCDC24 CNNM3 COX5B CYSRT1 DES DTNB DUSP21 FASLG FRS3 GOLGA6L2 GSTP1 HAPLN2 HDAC4 HGS HOXA1 INCA1 KDM1A KLC4 KRT1 KRT2 KRT3 KRT4 KRT6B KRT6C KRT71 KRT72 KRT75 KRT78 KRT79 KRT8 KRT80 KRT82 KRT83 KRT85 KRT86 LMO4 MOS NUP54 NUP58 PATZ1 PPP1R18 RAB26 RAMAC RTP5 RUNX1T1 SCNM1 SGF29 SHC3 USP2 VPS37C
Entrez ID		2950	3884
HPRD ID		00614	04136
Ensembl ID		ENSG00000084207	ENSG00000131738
Uniprot IDs		P09211 V9HWE9	Q14525
PDB IDs		10GS 11GS 12GS 13GS 14GS 16GS 17GS 18GS 19GS 1AQV 1AQW 1AQX 1EOG 1EOH 1GSS 1KBN 1LBK 1MD3 1MD4 1PGT 1PX6 1PX7 1ZGN 20GS 22GS 2A2R 2A2S 2GSS 2J9H 2PGT 3CSH 3CSI 3CSJ 3DD3 3DGQ 3GSS 3GUS 3HJM 3HJO 3HKR 3IE3 3KM6 3KMN 3KMO 3N9J 3PGT 4GSS 4PGT 5DAK 5DAL 5DCG 5DDL 5DJL 5DJM 5GSS 5J41 5JCW 5L6X 5X79 6AP9 6GSS 6Y1E 7GSS 8GSS 9GSS
Enriched GO Terms of Interacting Partners?
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