GSTM2 and GSTM3

Data Source:
HPRD (in vitro)

		GSTM2	GSTM3
Description		glutathione S-transferase mu 2	glutathione S-transferase mu 3
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GO Annotations	Cellular Component	Cytoplasm Cytosol Sarcoplasmic Reticulum Intercellular Bridge Extracellular Exosome	Nucleus Cytoplasm Cytosol Sperm Fibrous Sheath Intercellular Bridge Extracellular Exosome
	Molecular Function	Glutathione Transferase Activity Glutathione Peroxidase Activity Signaling Receptor Binding Fatty Acid Binding Protein Binding Enzyme Binding Protein Homodimerization Activity Glutathione Binding	Glutathione Transferase Activity Protein Binding Enzyme Binding Identical Protein Binding Protein Homodimerization Activity Glutathione Binding
	Biological Process	Glutathione Metabolic Process Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Nitrobenzene Metabolic Process Xenobiotic Catabolic Process Linoleic Acid Metabolic Process Hepoxilin Biosynthetic Process Relaxation Of Cardiac Muscle Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Cellular Detoxification Of Nitrogen Compound Cellular Response To Caffeine Cellular Oxidant Detoxification Glutathione Derivative Biosynthetic Process	Glutathione Metabolic Process Establishment Of Blood-nerve Barrier Nitrobenzene Metabolic Process Xenobiotic Catabolic Process Response To Estrogen Cellular Detoxification Of Nitrogen Compound Glutathione Derivative Biosynthetic Process
Pathways		Glutathione conjugation	Glutathione conjugation
Drugs		Glutathione S-(2,4-dinitrophenyl)glutathione Glutathione disulfide Glutathione disulfide S-Methyl glutathione	Glutathione Glutathione disulfide
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) HDL cholesterol levels ( 32203549) LDL cholesterol levels ( 32203549) Metabolite levels ( 31628463) Urinary metabolite levels in chronic kidney disease ( 31959995)	Blood protein levels ( 30072576)
Interacting Genes		4 interacting genes: GSTM1 GSTM3 GSTM5 PTEN	8 interacting genes: CLVS2 GSTM1 GSTM2 GSTM4 GSTM5 SH3GL2 UCHL5 YWHAE
Entrez ID		2946	2947
HPRD ID		00710	00712
Ensembl ID		ENSG00000213366	ENSG00000134202
Uniprot IDs		A0A384P5E9 P28161 Q0D2I8	P21266 Q6FGJ9
PDB IDs		1HNA 1HNB 1HNC 1XW5 1YKC 2AB6 2C4J 2GTU 3GTU 3GUR 5HWL	3GTU
Enriched GO Terms of Interacting Partners?
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