PDIA3 and ERP27

Data Source:
HPRD (in vitro, in vivo)

		PDIA3	ERP27
Description		protein disulfide isomerase family A member 3	endoplasmic reticulum protein 27
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GO Annotations	Cellular Component	Extracellular Space Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Lumen Focal Adhesion Cell Surface Melanosome MHC Class I Peptide Loading Complex Phagocytic Vesicle Recycling Endosome Membrane Extracellular Exosome	Endoplasmic Reticulum Endoplasmic Reticulum Lumen
	Molecular Function	RNA Binding Protein Disulfide Isomerase Activity Cysteine-type Endopeptidase Activity Phospholipase C Activity Protein Binding Disulfide Oxidoreductase Activity Peptide Disulfide Oxidoreductase Activity Identical Protein Binding	Protein Disulfide Isomerase Activity Protein Binding
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Protein Folding Proteolysis Protein Phosphopantetheinylation Protein Folding In Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Cellular Response To Interleukin-7 Positive Regulation Of Extrinsic Apoptotic Signaling Pathway	Protein Folding Response To Unfolded Protein Protein Phosphopantetheinylation Response To Endoplasmic Reticulum Stress
Pathways		ER-Phagosome pathway ER-Phagosome pathway Calnexin/calreticulin cycle Antigen Presentation: Folding, assembly and peptide loading of class I MHC Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs		Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Blood protein levels ( 30072576) Lead levels ( 26025379) Triglyceride levels ( 32203549)	Hand grip strength ( 29313844) Osteoarthritis of the hand ( 28855172)
Interacting Genes		21 interacting genes: APP BACE1 CALR CANX ERO1A ERP27 ESR1 GYPC HLA-A IFNG LGALS9 LINC01554 MDM2 MTNR1B PCAT1 SLC12A3 SLC2A1 STAT3 SUMO4 TAP1 UBE3A	11 interacting genes: BLOC1S2 C12orf60 EEF1D GOLGA8F MED20 PDIA3 SGTA UBL4A UBQLN1 UBQLN2 UBQLN4
Entrez ID		2923	121506
HPRD ID		03625	08723
Ensembl ID		ENSG00000167004	ENSG00000139055
Uniprot IDs		P30101 V9HVY3	F5GYS6 Q96DN0
PDB IDs		2ALB 2DMM 2H8L 3F8U 6ENY	2L4C 4F9Z
Enriched GO Terms of Interacting Partners?
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