GRP and GRPR

Data Source:
BioGRID (unspecified method)
HPRD (in vivo)

		GRP	GRPR
Description		gastrin releasing peptide	gastrin releasing peptide receptor
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Secretory Granule Lumen	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Signaling Receptor Binding Neuropeptide Hormone Activity Protein Binding	G Protein-coupled Receptor Activity Neuropeptide Receptor Activity G Protein-coupled Peptide Receptor Activity Neuropeptide Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Social Behavior Psychomotor Behavior Response To External Biotic Stimulus Positive Regulation Of Peptide Hormone Secretion Positive Regulation Of Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway	G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Learning Or Memory Social Behavior Psychomotor Behavior Regulation Of Cell Population Proliferation Response To External Biotic Stimulus Motor Behavior
Pathways		Peptide ligand-binding receptors Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) G alpha (q) signalling events	Peptide ligand-binding receptors G alpha (q) signalling events
Drugs
Diseases
GWAS		Adult body size ( 32376654) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 25673413) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Medication use (drugs used in diabetes) ( 31015401) Pancreatic cancer ( 29422604 26098869) Pancreatic ductal adenocarcinoma ( 30541042) Triglyceride levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Type 2 diabetes ( 30297969) Venous thromboembolism ( 32232851)	Lung function (FEV1/FVC) ( 26635082)
Interacting Genes		5 interacting genes: ALX1 DPP4 GRPR MEP1A MEP1B	1 interacting genes: GRP
Entrez ID		2922	2925
HPRD ID		08845	02376
Ensembl ID		ENSG00000134443	ENSG00000126010
Uniprot IDs		A0A140VJM7 P07492	P30550 X5D7H2
PDB IDs		2N0B 2N0C 2N0D 2N0E 2N0F 2N0G 2N0H
Enriched GO Terms of Interacting Partners?
Tagcloud ?
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Tagcloud (Intersection) ?