GRM3 and PPM1A

  • Data Source:
  • HPRD (in vitro)

GRM3

PPM1A

Description glutamate metabotropic receptor 3 protein phosphatase, Mg2+/Mn2+ dependent 1A
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Asthma ( 27611488)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Brachial circumference ( 22479309)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Feeling worry ( 29500382)
  • Hand grip strength (Mahalanobis distance) ( 32235003)
  • Neurociticism ( 29500382)
  • Neuroticism ( 29255261)
  • Refractive error ( 32231278)
  • Schizophrenia ( 28991256 25056061 29483656 30285260)
  • Seborrheic dermatitis ( 29203360)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
  • Allergic rhinitis ( 22036096)
  • Blond vs. brown/black hair color ( 30531825)
  • Chronotype ( 30696823)
  • Diastolic blood pressure ( 30224653)
  • Hair color ( 29662168)
  • Hip circumference adjusted for BMI ( 25673412)
  • Menarche (age at onset) ( 27182965)
  • Refractive error ( 32231278)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes 6 interacting genes: CALM1 GRIP1 PICK1 PPM1A SDCBP TAMALIN 37 interacting genes: AATK AKT1 ALK CACNA1A CACNA1B CACNA1C CDC42BPA CDC42BPB CTNNB1 DVL1 DVL2 DVL3 EEF2 EGFR ERBB2 ERBB3 ERBB4 FGFR2 GRM3 HSPB1 IGF1R KDR LMTK2 MSN NR4A1 PAK1 PAK2 PIK3R1 PLK3 PRKAA1 PRKCA PRKCD PTK7 ROR2 RPLP0 SMAD2 SMAD3
Entrez ID 2913 5494
HPRD ID 03070 16199
Ensembl ID ENSG00000198822 ENSG00000100614
Uniprot IDs A4D1D0 Q14832 A0A024R6A5 B2R8E4 P35813
PDB IDs 1S8M 3SM9 4XAR 5CNK 5CNM 6B7H 1A6Q 3FXJ 3FXK 3FXL 3FXM 3FXO 4RA2 4RAF 4RAG 6B67
Enriched GO Terms of Interacting Partners?
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