GRIN2B and GRIN1

  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo)

GRIN2B

GRIN1

Description glutamate ionotropic receptor NMDA type subunit 2B glutamate ionotropic receptor NMDA type subunit 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adventurousness ( 30643258)
  • Aging (time to event) ( 21782286)
  • Alzheimer's disease in hypertension ( 31055733)
  • Brain structure (temporal lobe volume) ( 20197096)
  • Cellular nuclear factor (erythroid-derived 2)-like 2 levels ( 30767168)
  • Cerebrospinal AB1-42 levels in normal cognition ( 29274321)
  • Cognitive performance ( 19734545)
  • Dietary fat liking ( 32516399)
  • Egg allergy (parent-of-origin effect) ( 29489655)
  • General risk tolerance (MTAG) ( 30643258)
  • Height ( 31562340)
  • Immune reponse to smallpox (secreted IL-2) ( 22610502)
  • Major depressive disorder ( 23377640)
  • Ovarian reserve ( 22116950)
  • Refractive error ( 32231278)
  • Response to selective serotonin reuptake inhibitors in depression ( 30034349)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
  • Systolic blood pressure ( 30224653)
  • Total ventricular volume ( 21116278)
  • Waist-hip ratio ( 28552196)
  • Waist-to-hip ratio adjusted for BMI ( 28552196)
  • Post-traumatic stress disorder (asjusted for relatedness) ( 23726511)
Interacting Genes 43 interacting genes: ACTN2 AP1M1 AP2M1 AP4M1 ARHGAP32 CAMK2A CAMK2B CAMK2D CAMK2G CAMK2N1 CAPN1 DLG1 DLG2 DLG3 DLG4 EGFR EPHB2 ERBIN EXOC4 EXOC7 FYN GRIN1 GRIN2A GRIN3A IL16 LIN7A LIN7B MAGI3 MIB2 PATJ PIK3CA PLCG1 PRKCA PRKCB PRKCG PRKN PTPN11 RACK1 RASGRF1 SPTAN1 SRC SYNGAP1 TANC1 57 interacting genes: ACTN2 AKAP9 APP BDKRB1 CALM1 CAMK2A CAMK2G CANX CDH2 CIT CLTC CTNNB1 DLG1 DLG2 DLG3 DLG4 DLGAP4 DNM1 DRD1 DUSP4 EPHB2 EPHB4 FUS FYN GRIN2A GRIN2B GRIN2D GRIN3A HNRNPU HRAS HSPA1A INA LNX1 LRP8 MAP2 MAP2K2 MYH9 NANOS1 NEFL NF1 PLAT PLCG1 PPP2R1A PPP2R2A PRKCA PRKCB PRKCE PRKCG PTAFR RAP2A RPS6KA3 SP3 SPTAN1 SYNGAP1 TJP1 TRAF3 TUBA4B
Entrez ID 2904 2902
HPRD ID 00697 15926
Ensembl ID ENSG00000273079 ENSG00000176884
Uniprot IDs Q13224 Q05586 Q59GW0 Q5VSF9
PDB IDs 1S11 1S2S 2IPV 5EWJ 5EWL 5EWM 2HQW 2NR1 3BYA 5H8F 5H8H 5H8N 5H8Q 5I2K 5I2N 5KCJ 5KDT 5TP9 5TPA 6IRA 6IRF 6IRG 6IRH
Enriched GO Terms of Interacting Partners?
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